- Synthesis of 2-(arylamino)nicotinic acids in high-temperature water
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In hydrothermal reactions at 150-180 °C, 2-(arylamino)nicotinic acids were synthesized by amination of 2-chloronicotinic acid with aromatic amine derivatives, with potassium carbonate as base. The procedure is efficient, environmentally friendly, and practical, with moderate to excellent yields (up to 98%). Springer Science+Business Media B.V. 2012.
- Li, Zhenghua,Xiao, Shangyou,Liang, Ronghui,Xia, Zhining
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p. 1691 - 1697
(2012/10/29)
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