- Preparation method of ceftizoxime intermediate 7-ANCA
-
The invention provides a preparation method of ceftizoxime intermediate 7-ANCA. 7-ACCA is adopted as a starting material, and subjected to reduction of a No.3-site double bond, iodine substitution andan elimination reaction to obtain the 7-ANCA. The metho
- -
-
-
- Synthesis method of ceftizoxime mother nucleus 7-ANCA
-
The invention discloses a synthesis method of ceftizoxime mother nucleus 7-ANCA. With CHS as a staring raw material, reduction of hydroxyl groups and removal of amino protection groups, namely, phenylacetyl groups on 7 bits and protection groups, namely,
- -
-
Paragraph 0035; 0036; 0037
(2016/12/12)
-
- A 7 - aNCA method for the preparation of (by machine translation)
-
The present invention provides a synthetic Cefixime and Cefprozil important intermediate 7 - ANCA process, in order to 7 - ACA as raw materials, the amino protection, hydrolysis, cracking and deaminizating protection base 7 - ANCA, molar yield ≥ 54% (in order to 7 - ACA calculation), the operation is simple, the number of reaction steps is small, the current process in the middle part of the expensive raw materials, product quality is poor, phosphorus-containing waste, and the like, is suitable for industrial production. (by machine translation)
- -
-
-
- 7β-Amino-cepham-3-ol-4-carboxylic acid compounds
-
The invention concerns 7β-amino-cepham-3-ol-4-carboxylic acid compounds, particularly esters thereof, and the N-substituted, especially N-acylated derivatives of such compounds, as well as the 3-O-esters of these compounds. They can be used as intermediates, for example, for the manufacture of the corresponding 3-unsubstituted 7β-amino-3-cephem-4-carboxylic acid compounds, which show outstanding pharmacological effects.
- -
-
-