36923-17-8 Usage
Description
7-Amino-3-cephem-4-carboxylic acid, also known as 7-ACA, is an important intermediate compound in the synthesis of cephalosporin antibiotics. It is an off-white solid with chemical properties that make it a crucial component in the pharmaceutical industry. Its structure allows for the attachment of various side chains, which can enhance the antibiotic properties of the final product.
Uses
Used in Pharmaceutical Industry:
7-Amino-3-cephem-4-carboxylic acid is used as a key intermediate for the production of cephalosporin antibiotics. These antibiotics are widely used to treat a range of bacterial infections due to their broad-spectrum activity and low toxicity. The versatility of 7-ACA allows for the development of new cephalosporin derivatives with improved properties, such as increased potency, better stability, and reduced side effects.
Used in Research and Development:
In addition to its role in the pharmaceutical industry, 7-Amino-3-cephem-4-carboxylic acid is also used as a research tool for studying the structure-activity relationships of cephalosporin antibiotics. This helps scientists understand how modifications to the 7-ACA molecule can lead to the development of more effective and safer antibiotics.
Used in Quality Control:
7-Amino-3-cephem-4-carboxylic acid is employed as a reference standard in the quality control of cephalosporin antibiotics. It is used to ensure that the synthesized antibiotics meet the required purity and potency standards, which is crucial for their effectiveness and safety in clinical use.
Check Digit Verification of cas no
The CAS Registry Mumber 36923-17-8 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 3,6,9,2 and 3 respectively; the second part has 2 digits, 1 and 7 respectively.
Calculate Digit Verification of CAS Registry Number 36923-17:
(7*3)+(6*6)+(5*9)+(4*2)+(3*3)+(2*1)+(1*7)=128
128 % 10 = 8
So 36923-17-8 is a valid CAS Registry Number.
InChI:InChI=1/C7H8N2O3S/c8-4-5(10)9-3(7(11)12)1-2-13-6(4)9/h1,4,6H,2,8H2,(H,11,12)/t4-,6-/m1/s1
36923-17-8Relevant articles and documents
Preparation method of ceftizoxime intermediate 7-ANCA
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, (2019/11/21)
The invention provides a preparation method of ceftizoxime intermediate 7-ANCA. 7-ACCA is adopted as a starting material, and subjected to reduction of a No.3-site double bond, iodine substitution andan elimination reaction to obtain the 7-ANCA. The metho
A 7 - aNCA method for the preparation of (by machine translation)
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, (2017/05/02)
The present invention provides a synthetic Cefixime and Cefprozil important intermediate 7 - ANCA process, in order to 7 - ACA as raw materials, the amino protection, hydrolysis, cracking and deaminizating protection base 7 - ANCA, molar yield ≥ 54% (in order to 7 - ACA calculation), the operation is simple, the number of reaction steps is small, the current process in the middle part of the expensive raw materials, product quality is poor, phosphorus-containing waste, and the like, is suitable for industrial production. (by machine translation)
New β lactam antibiotics. Preparation and decarbonylation of 3 formylcephem compounds
Peter,Bickel
, p. 2044 - 2054 (2007/10/05)
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