- Biodegradable copolyester of 4-hydroxy proline and pharmaceutical composition containing the same
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A biodegradable copolymer having the constituent units derived from 4-hydroxyproline and an aliphatic α-hydroxycarboxylic acid, represented by the structures (I) and (II): wherein X represents a hydrogen atom, an acyl group having the formula RCO- where R is a hydrocarbon or an alkoxy group having 1 to 20 carbon atoms, and Y represents a hydrogen atom or an alkyl group having 1 to 8 carbon atoms, and m and n are independently integers of 1 or more, m + n is at least 10, and m/(m + n) is at least 0.01 and a pharmaceutical composition containing the same.
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- HIGHER N-ACYL-L-AMINO ACID DERIVATIVES
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A preparative method is proposed for obtaining higher N-acylamino acids by reaction of free amino acids with fatty acid nitrophenyl esters.It was shown that these acids can transport positive ions through a liquid lipophilic medium.A direct method is proposed for obtaining fatty acid 4-nitrophenyl esters by boiling 4-nitrophenol and the fatty acid in xylene in a Soxhlet apparatus in the presence of an acid catalyst.
- Kochetkov, K. A.,Urmambetova, Zh. S.,Belikov, V. M.,Bakasova, Z. B.
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p. 2311 - 2316
(2007/10/02)
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