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452-79-9

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COMPOUND HAVING 2-FLUOROPHENYLOXYMETHANE STRUCTURE
The present invention relates to a compound having a 2-fluorophenyloxymethane structure and useful for organic electronic materials and medical and agricultural chemicals, particularly materials for liquid crystal display elements. A problem to be solved
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Paragraph 0166; 0167

(2014/09/30)

4-[2,3-DIFLUORO-6-(2-FLUORO-4-METHYL-PHENYLSULFANYL)-PHENYL]-PIPERIDINE
The compound 4-[2,3-Difluoro-6-(2-fluoro-4-methyl-phenylsulfanyl)-phenyl]-piperidine according to the structure (formula I), and pharmaceutically acceptable salts thereof are provided for the treatment of CNS related disorders, such as : depressive disord
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Page/Page column 16; 17

(2009/07/18)

PROTEIN TYROSINE PHOSPHATASE INHIBITORS AND METHODS OF USE THEREOF
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Page/Page column 87-88

(2008/06/13)

Synthesis of chiral building blocks for use in drug discovery
In the past decade there has been a significant growth in the sales of pharmaceutical drugs worldwide, but more importantly there has been a dramatic growth in the sales of single enantiomer drugs. The pharmaceutical industry has a rising demand for chiral intermediates and research reagents because of the continuing imperative to improve drug efficacy. This in turn impacts on researchers involved in preclinical discovery work. Besides traditional chiral pool and resolution of racemates as sources of chiral building blocks, many new synthetic methods including a great variety of catalytic reactions have been developed which facilitate the production of complex chiral drug candidates for clinical trials. The most ambitious technique is to synthesise homochiral compounds from non-chiral starting materials using chiral metal catalysts and related chemistry. Examples of the synthesis of chiral building blocks from achiral materials utilizing asymmetric hydrogenation and asymmetric epoxidation are presented.
Marino, Sharon T.,Stachurska-Buczek, Danuta,Huggins, Daniel A.,Krywult, Beata M.,Sheehan, Craig S.,Nguyen, Thao,Choi, Neil,Parsons, Jack G.,Griffiths, Peter G.,James, Ian W.,Bray, Andrew M.,White, Jonathan M.,Boyce, Rustum S.
p. 405 - 426
(2007/10/03)

1,2,4-triazole based compounds that can be used as insecticides or acaricides and processes
3-(Substituted aryl)-5-{substituted aryl-(alkynyl-aryl)}-[1,2,4]- triazole compounds are useful as insecticides and acaricides. New synthetic procedures and intermediates for preparing the compounds, pesticide compositions containing the compounds, and me
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(2008/06/13)

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Chemical Properties

Appearance/Colour :colorless to light yellow liqui
Boiling Point: 138-139 °C9 mm Hg(lit.)
Flash Point:92 ºC
Density: 1.803
Storage Temp.:Keep in dark place,Sealed in dry,Room Temperature
Vapor Pressure: 0.285mmHg at 25°C
Refractive Index: n20/D 1.5810(lit.)
Sensitive: Light Sensitive
PSA: 0.00000
LogP: 2.73870

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