Organocatalytic Allylic Amination of Morita-Baylis-Hillman Carbonates
An organocatalytic asymmetric allylic amination of Morita-Baylis-Hillman carbonates with aromatic amines in the presence of β-isocupreidine is described. Chiral allylic amines were obtained in almost quantitative yields (90-96%) with moderate enantioselectivity. Recrystallization afforded products in good yields (45-73%) and high optical purity (82-99% ee). This method provides a facile and efficient route to obtain optically active β-lactams, including the building block of the cholesterol-lowering drug Ezetimibe.
Formánek, Bed?ich,?imek, Michal,Kamlar, Martin,Císa?ová, Ivana,Vesely, Jan
p. 907 - 920
(2019/02/10)
Silver ion mediated in situ synthesis of mixed diaryl sulfides from diaryl disulfides
The AgNO3-mediated in situ scission of aromatic disulfides in the presence of electron-rich aromatic compounds results in the efficient synthesis of diaryl sulfides. Key features of this new methodology are high yields of aromatic and heteroaromatic sulfides, mild reaction conditions, simplicity, simple workup, and avoiding foul-smelling reactants like thiols. Georg Thieme Verlag Stuttgart · New York.
The orthopalladation of aniline via its 2-nitrophenylsulfenyl derivative
2-Nitrophenylsulfenylanilide can be orthopalladated to give μ,μ-dichlorodipalladium-bis(2-nitrophenylsulfenylanilide), which on carbometoxylation gives 2-nitrophenylsulfenylanthranylate.
Guarnieri, A.,Parkins, A. W.
p. 399 - 404
(2007/10/02)
Ortho Effects in Organic Molecules on Electron Impact: 21 - Oxygen Transfers from the Ortho Nitro Group to Sulphur in N-Aryl-2-nitrobenzenesulphenamides and Phenyl-2-nitrophenyl Disulphide
Fragment ions arising as a result of oxygen transfer from the nito group to sulphur have been noticed in N-aryl-2-nitrobenzenesulphenamides and phenyl-2-nitrophenyl disulphide.In the case of the former a double oxygen transfer to the sulphur has been noti
Ramana, D. V.,Sundaram, N.,George, M.
p. 926 - 930
(2007/10/02)
PARTICIPATION OF ELECTRONIC ORGANIC COMPOUNDS OF DIVALENT SULFUR IN CATALYTIC CONVERSIONS. II. CATALYTIC EXCHANGE REACTION OF N-MONOSULFENYLATED AMINES WITH S-ESTERS OF THIOCARBOXYLIC ACID
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Parfenov, E. A.,Fomin, V. A.
p. 947 - 953
(2007/10/02)
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