cas 54779-53-2, 9-aminoellipticine | Articles data ｜lookchem

Welcome to LookChem.com Sign In|Join Free

Article Database

Home > CAS Article list >
54779-53-2

Articles about 54779-53-2Total 3 be found

Article title
Article abstract
Author
Journal number and time
Download

On 9-amino derivatives of ellipticine and a comparative study on DNA apurinic site cleavage and mutagenicity
The synthesis of 9-aminoellipticine (IV) has been improved by amination of 9-bromoellipticine according to the Goldberg reaction. Also via the Goldberg procedure we obtained 9-methylamino-ellipticine (VI) with the aim to reduce the mutagenicity of (IV). Even though 2-methyl-9-aminoellipticinium acetate (VII) has been mentioned in a previous paper, no details were given for its preparation. We therefore synthesized this compound in such a way as to obtain a monoquaternary salt where only the pyridinic nitrogen bears the positive charge. The study of cleavage induced by 10 μM of (IV) and (VII) on a plasmid DNA (PM2) containing a low concentration of apurinic sites shows that (VII) possesses the same property of cleavage at apurinic sites as (IV) and reaches almost complete cleavage despite its slower reaction rate. The quaternized derivative (VII) is not mutagenic on tested Salmonella strains in contrast with its free base (IV).
Lefrancois,Lescot,Psaume,Malvy,Gansser,Virlizier,Boissart,Gauduchon
p. 1197 - 1206
(2007/10/02)

9-nitro and 9-aminoellipticines and derivatives: Synthesis and pharmaceutical properties
-
Gansser,Viel,Malvy,Cros
p. 887 - 895
(2007/10/02)

9 Hydroxyellipticine and some of its derivatives
-
Dat Xuong,Adeline,Lecointe,Janot
p. 623 - 626
(2007/10/05)

More Articles about upstream products of 54779-53-2

More Articles about downstream products of 54779-53-2

148528-69-2
2-methyl-9-aminoellipticinium acetate

Chemical Properties

Boiling Point: 565.6°C at 760 mmHg
Flash Point:330.5°C
Density: 1.318g/cm³
Vapor Pressure: 8.18E-13mmHg at 25°C
Refractive Index: 1.6360 (estimate)
PSA: 54.70000
LogP: 4.64950

Show more

Global suppliers and manufacturers of 54779-53-2total 6 suppliers on LookChem

Company Name
Business Type
Min Order
FOB Price
Main Products
Contact

Dayang Chem (Hangzhou) Co.,Ltd.
Business Type:Lab/Research institutions
Min Order:1 Kilogram
FOB Price:USD $ 3.0-3.0 / Kilogram
Main Products:994
Country:

Shandong Mopai Biotechnology Co., LTD
Business Type:Lab/Research institutions
Min Order:1 Gram
FOB Price:No Data
Main Products:60
Country:

Antimex Chemical Limied
Business Type:Lab/Research institutions
Min Order:No Data
FOB Price:No Data
Main Products:163
Country:

Henan Tianfu Chemical Co., Ltd.
Business Type:Lab/Research institutions
Min Order:No Data
FOB Price:No Data
Main Products:67
Country:

BOC Sciences
Business Type:Trading Company
Min Order:No Data
FOB Price:No Data
Main Products:41
Country:

Hangzhou Fandachem Co.,Ltd
Business Type:Other
Min Order:No Data
FOB Price:No Data
Main Products:52
Country:

Post a RFQ

Cas No.:

Product Name:

Quantity:

Email:

Company name:

Valid Period:

Detailed Requirements:

Enter 15 to 2000 letters.Word count: 0 letters

Attach files(File Format: Jpeg, Jpg, Gif, Png, PDF, PPT, Zip, Rar,Word or Excel Maximum File Size: 3MB)

1

What can I do for you?
Get Best Price

Get Best Price for 54779-53-2

About us - Payment - Contact us - Links - Help Center - Disclaimer
SiteMap | Manufacturers | VIP Product | Suppliers | CAS | New CAS | Cas Database | Article Data | Chemical Catalog | Product Name

©2008 LookChem.com,License:ICP NO.:Zhejiang16009103 complaints:service@lookchem.com
[Hangzhou]86-571-87562588,87562561,87562573 Our Legal adviser: Lawyer