- The effect of the phosphoryl group on the rate and mechanism of SN-substitution at the saturated carbon atoms
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The reactivity of diarylphosphine oxides RR'P(O)CH2X with p-O2NC6H4ONa in DMF have been studied.The reaction rate increases with the electrodrawing properties of the substituents on R and R' in the following way: p-Me2NC6H4 2 reaction rate of diphenylphosphine oxides has been investigated.The reactivity increases as follows Cl I Br OTs.A reaction mechanism is suggested.
- Tsvetkov, E. N.,Tkachenko, S. E.,Yarkevich, A. N.
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p. 339 - 341
(2007/10/02)
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- Production of tertiary (hydroxymethyl)-methylphosphine oxides
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Production of tertiary (hydroxymethyl)-methylphosphine oxides of the general formula: STR1 in which R stands for a branched or unbranched, substituted or unsubstituted alkyl, cycloalkyl, aralkyl or aryl group having from 1 to 18 carbon atoms. To this end tertiary bis-(hydroxymethyl)-phosphines of the general formula STR2 in which R has the meaning given above, are subjected to a thermal rearrangement reaction at temperatures higher than about 90° C or at temperatures within the range -10° and +250° C, in the presence of a catalyst.
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- Production of methylphosphine oxides
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Methylphosphine oxides of the general formula (I) EQU1 are produced from hydroxymethylphosphines of the general formula (II) EQU2 in which formulae R and R' each stand for identical or different alkyl-, cycloalkyl-, aralkyl- or aryl groups having from 1 to 18 carbon atoms, or carrying substituents being inert under the reaction conditions. The methylphosphine oxides are more particularly produced by subjecting the hydroxymethylphosphines to a rearrangement reaction with the aid of radical-yielding compounds.
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