Synthesis of 2-chloro-4-nitrophenyl α-L-fucopyranoside: A substrate for α-L-fucosidase (AFU)
An effective method to prepare the substrate of α-L-fucosidase (AFU) is described. Ethyl 1-thiofucoside with a free 2-OH group was used as the glycosyl donor, and there was found no self-condensed side product. The use of the HF·pyridine reagent to remove