Generation of an 4-Isoxazolyl Anion Species: Facile Access to Multifunctionalized Isoxazoles
A direct functionalization of unsubstituted isoxazole (1) was achieved by generation of 4-isoxazolyl anion species (3). An efficient 4-iodination of isoxazole and halogen–metal exchange reaction using a turbo Grignard reagent (iPrMgCl? LiCl) were essentia
Morita, Taiki,Fuse, Shinichiro,Nakamura, Hiroyuki
supporting information
p. 13580 - 13584
(2016/10/21)
ISOLATION, STRUCTURE AND SYNTHESIS OF 4-HYDROXYISOXAZOLE (TRIUMFEROL), A SEED GERMINATION INHIBITOR FROM AN AFRICAN PLANT
The isolation, characterization and an efficient synthesis of 4-hydroxyisoxazole 1, a plant growth regulator isolated from an African plant is reported.It is a new compound, which despite the simple structure, had eluded synthesis.