The present invention provides a method of treatment or prophylaxis of a viral infection in a subject comprising administering to said subject an effective amount of a compound of formula (I) or a pharmaceutically acceptable derivative, salt or prodrug thereof. Compounds of formula (I) are also provided.
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Page/Page column 61
(2008/06/13)
Efficient Synthesis of 4-Acylisoxazole Derivatives from Triformylmethane
We show that a number of 4-substituted isoxazoles (4-cyano, 4-ethoxycarbonyl) can be prepared efficiently from either triformylmethane or its trisdimethylimino precursor.We also report the preparation of cyano(formyl)acetamidine, a compound containing three different functional groups attached to one carbon atom.
Angus, Richard O.,Bryce, Martin R.,Keshavarz-K., M.,Wudl, Fred
p. 746 - 748
(2007/10/02)
ISOLATION, STRUCTURE AND SYNTHESIS OF 4-HYDROXYISOXAZOLE (TRIUMFEROL), A SEED GERMINATION INHIBITOR FROM AN AFRICAN PLANT
The isolation, characterization and an efficient synthesis of 4-hydroxyisoxazole 1, a plant growth regulator isolated from an African plant is reported.It is a new compound, which despite the simple structure, had eluded synthesis.