Chemoselective Transfer Hydrogenation of Enamides Using Ru Pincer Complexes for the Synthesis of α-Amino Acids
The chemoselective reduction of enamides to α-amino acids with iPrOH and EtOH as H-donors and solvents catalyzed by Ru pincer complexes is demonstrated. A range of α-amino acids is synthesized in good to excellent yields. Applications, large scale, and a one-pot experiment are also reported. Finally, deuterium-labeling experiments show high regioselectivity between the α-and β-positions of the alkene unit.
Pinheiro, Danielle L. J.,Nielsen, Martin
p. 5419 - 5423
(2022/03/14)
PROCESS FOR MANUFACTURE OF N-ACYLBPHENYL ALANINE
A novel process, novel process steps and novel intermediates useful in the synthesis of pharmaceutically active compounds, in particular neutral endopeptidase (NEP) inhibitors.
-
Page/Page column 12
(2011/04/24)
PROCESS FOR THE MANUFACTURE OF N-ACYLBIPHENYL ALANINE
A novel process, novel process steps and novel intermediates useful in the synthesis of pharmaceutically active N-acylbiphenyl alanine compounds, in particular neutral endopeptidase (NEP) inhibitors.
-
Page/Page column 14
(2010/04/27)
Efficient and chemoselective conversion of aryl aldehydes to their azalactones catalysed by Bi(III) salts under solvent free conditions
Bi(NO3)3.5H2O, Bi(TFA)3 and Bi(OTf)3 were found to be highly powerful and practical catalysts for the synthesis of azalactones under solvent free conditions with excellent yields. In addition, high ch
Khodaei, Mohammad Mehdi,Khosropour, Ahmad Reza,Jomor, Saied Jabar Hoseini
p. 638 - 641
(2007/10/03)
More Articles about upstream products of 66404-26-0