66404-26-0

Basic information

• Product Name: 5(4H)-Oxazolone, 4-([1,1'-biphenyl]-4-ylmethylene)-2-phenyl-
• CAS NO: 66404-26-0
• Molecular Formula: C22H15NO2
• Molecular Weight: 325.367
• Mol File: 66404-26-0.mol
• Article Data: 4

Chemical Properties

• CAS DataBase Reference: 5(4H)-Oxazolone, 4-([1,1'-biphenyl]-4-ylmethylene)-2-phenyl-(CAS DataBase Reference)
• NIST Chemistry Reference: 5(4H)-Oxazolone, 4-([1,1'-biphenyl]-4-ylmethylene)-2-phenyl-(66404-26-0)
• EPA Substance Registry System: 5(4H)-Oxazolone, 4-([1,1'-biphenyl]-4-ylmethylene)-2-phenyl-(66404-26-0)

Safety Data

• Hazardous Substances Data: 66404-26-0(Hazardous Substances Data)

Upstream product

• 495-69-2 Hippuric Acid 
• 3218-36-8 4-Phenylbenzaldehyde 
• 98-88-4 benzoyl chloride 
• 1667-11-4 biphenyl-4-methylchloride 

Downstream Products

• 84019-95-4 2-Phenyl-4-(4-phenylbenzylidene)imidazol-5-one 
• 91853-46-2 3-([1,1'-biphenyl]-4-yl)-2-oxopropanoic acid 

Relevant articles and documents

Chemoselective Transfer Hydrogenation of Enamides Using Ru Pincer Complexes for the Synthesis of α-Amino Acids

The chemoselective reduction of enamides to α-amino acids with iPrOH and EtOH as H-donors and solvents catalyzed by Ru pincer complexes is demonstrated. A range of α-amino acids is synthesized in good to excellent yields. Applications, large scale, and a one-pot experiment are also reported. Finally, deuterium-labeling experiments show high regioselectivity between the α-and β-positions of the alkene unit.

PROCESS FOR THE MANUFACTURE OF N-ACYLBIPHENYL ALANINE

A novel process, novel process steps and novel intermediates useful in the synthesis of pharmaceutically active N-acylbiphenyl alanine compounds, in particular neutral endopeptidase (NEP) inhibitors.