- Phenyl-imidazolo-cytidine analogues: Structure-photophysical activity relationship and ability to detect single dna mismatch
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To expand the arsenal of fluorescent cytidine analogues for the detection of genetic material, we synthesized para-substituted phenyl-imidazolo-cytidine (PhImC) analogues 5a-g and established a relationship between their structure and fluoresce
- Kovaliov, Marina,Weitman, Michal,Major, Dan Thomas,Fischer, Bilha
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p. 7051 - 7062
(2014/08/18)
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- Fluorescent p-substituted-phenyl-imidazolo-cytidine analogues
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The synthesis and spectral properties of modified cytidine analogues are described here. To confer fluorescent properties, the cytidine fluorophore was extended by a cinnamyl moiety at the cytidine 5-position, (analogues 1a-c), or extended by a phenyl-imi
- Kovaliov, Marina,Segal, Meirav,Fischer, Bilha
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p. 3698 - 3705
(2013/05/08)
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- Mapping the landscape of potentially primordial informational oligomers: Oligodipeptides tagged with 2,4-disubstituted 5-aminopyrimidines as recognition elements
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(Chemical Equation Presented) Bit different: 2,4-Dioxo- and 2,4-diamino-5-aminopyrimidine nuclei attached to an oligodipeptide backbone display a disparity in their base-pairing strength which is opposite to that shown by corresponding triazines. This behavior points to a remarkable correlation between pairing strength and ΔpKa values of pairs of complementary bases.
- Mittapalli, Gopi Kumar,Osornio, Yazmin M.,Guerrero, Miguel A.,Reddy, Kondreddi Ravinder,Krishnamurthy, Ramanarayanan,Eschenmoser, Albert
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p. 2478 - 2484
(2008/03/11)
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- Regioselective Addition of Grignard Reagents to a 2-Oxopurinium Salt
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Treatment of 6-ethoxy-1,3,6,7-tetrahydro-1,3,7-tribenzyl-2H-purin-2-one with trimethylchlorosilane gave a stable tribenzylated 2-oxopurinium salt, which selectively added Grignard reagents in the 6-position.The structure of the adducts were established fr
- Andresen, Geir,Gundersen, Lise-Lotte,Lundmark, Max,Rise, Frode,Sundell, Staffan
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p. 3655 - 3664
(2007/10/02)
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