Synthesis and properties of some 13-cis- and all-trans-retinamides
Several 13-cis-retinamides were synthesized from 13-cis-retinoic acid via either 13-cis-retinoyl chloride or 13-cis-1-retinoylimidazole. All-trans-retinoylglycine was prepared from all-trans-retinoyl chloride and ethyl glycinate. Detailed procedures were developed for the preparation of other all-trans-retinamides on a large scale for studies of the chemoprevention of cancer.
Shealy,Frye,O'Dell,Thorpe,Kirk,Coburn Jr.,Sporn
p. 745 - 751
(2007/10/02)
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