- 1H-1,3-benzazaphospholes: The organometallic route and a new three-step synthesis with reductive ring closure
-
Primary and N-secondary 2-phosphanylanilines were synthesized via metallation of 2-bromoanilines, coupling with CIP(NMe2)2, alcoholysis and reduction with LiAlH4, and subsequently reacted with formimidoester hydrochloride to give 1,3-benzazaphospholes. For 1H-1,3-benzazaphospholes, a shorter alternative three-step synthesis was developed, based on N-acylation of 2-bromoaniline, NiCl2-catalyzed arylation of triethyl phosphite and a new reductive cyclization of amidophosphonic acid ester with excess LiAlH4.
- Bansal, Raj K.,Gupta, Neelima,Heinicke, Joachim,Nikonov, George N.,Saguitova, Farida,Sharma, Dinesh C.
-
p. 264 - 269
(2007/10/03)
-
- Reactions of o-Lithio-lithiumphenolate and o-Lithio-N-methyl-lithiumanilide with Halides of Phosphorus, Arsenic and Silicon
-
The title compounds and chlorides of the type ClERn (E=P, As, Si) react smoothly in a molecular ratio of 1:2 to give the corresponding disubstituted phenole and N-methylaniline derivatives, respectively.Attempts with an 1:1 ratio show different results de
- Heinicke, J.,Tzschach, A.
-
p. 232 - 237
(2007/10/02)
-