84759-21-7

Basic information

• Product Name: C₁₅H₃₁N₅P₂
• CAS NO: 84759-21-7
• Molecular Weight: 343.392
• Mol File: 84759-21-7.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: C₁₅H₃₁N₅P₂(CAS DataBase Reference)
• NIST Chemistry Reference: C₁₅H₃₁N₅P₂(84759-21-7)
• EPA Substance Registry System: C₁₅H₃₁N₅P₂(84759-21-7)

Safety Data

• Hazardous Substances Data: 84759-21-7(Hazardous Substances Data)

Upstream product

• 6832-87-7 2-bromo-N-methylaniline 
• 3348-44-5 bis(N,N-dimethylamino)chlorophosphine 

Downstream Products

• 84759-27-3 1-methyl-2-phenyl-1,3-benzazaphosphole 
• 84759-23-9 o-Phospholino-N-methylanilin 
• 84759-22-8 N-methylaminobenzenephosphonous acid diethyl ester 

Relevant articles and documents

1H-1,3-benzazaphospholes: The organometallic route and a new three-step synthesis with reductive ring closure

Primary and N-secondary 2-phosphanylanilines were synthesized via metallation of 2-bromoanilines, coupling with CIP(NMe2)2, alcoholysis and reduction with LiAlH4, and subsequently reacted with formimidoester hydrochloride to give 1,3-benzazaphospholes. For 1H-1,3-benzazaphospholes, a shorter alternative three-step synthesis was developed, based on N-acylation of 2-bromoaniline, NiCl2-catalyzed arylation of triethyl phosphite and a new reductive cyclization of amidophosphonic acid ester with excess LiAlH4.