cas 868049-49-4, 6-Hydroxy-8-[(1R)-1-hydroxy-2-[[2-(4-methoxyphenyl)-1,1-dimethylethyl]amino]ethyl]-2H-1,4-benzoxazin-3(4H)-one

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Olodaterol hydrochloride crystal form A and preparation method thereof
The invention relates to a long-acting beta 2 adrenergic agonist drug olodaterol hydrochloride crystal form A, a preparation method thereof and and a pharmaceutical composition containing the crystalform A. The crystal form is characterized by X-ray diffr
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(2019/01/16)

Discovery of olodaterol, a novel inhaled β2-adrenoceptor agonist with a 24 h bronchodilatory efficacy
Compound 4p was identified from a series of 6-hydroxy-4H-benzo[1,4]oxazin-3-ones as potent agonist of the human β2-adrenoceptor with a high β1/β2-selectivity. A complete reversal of acetylcholine-induced bronchoconstrictio
Bouyssou, Thierry,Hoenke, Christoph,Rudolf, Klaus,Lustenberger, Philipp,Pestel, Sabine,Sieger, Peter,Lotz, Ralf,Heine, Claudia,Büttner, Frank H.,Schnapp, Andreas,Konetzki, Ingo
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p. 1410 - 1414
(2010/07/10)

PROCESS FOR THE MANUFACTURING OF BETAMIMETICS
The present invention relates to a process for preparing betamimetics of formula 1, wherein n denotes 1 or 2; R1 denotes hydrogen, halogen, C1-4-alkyl or O—C1-4-alkyl; R2 denotes hydrogen, halogen, C1-4/su
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Page/Page column 12

(2008/06/13)

New enentiomerically pure beta agonists, process for the manufacture thereof and use thereof as medicaments
The present invention relates to enantiomerically pure compounds of general formula 1 wherein the groups R1, R2, R3, R4 and X? may have the meanings given in the claims and in the specification, proce
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Page/Page column 9-10

(2008/06/13)

NOVEL ENANTIOMERICALLY PURE BETA-AGONISTS, METHOD FOR THE PRODUCTION AND THE USE THEREOF IN THE FORM OF A DRUG
The invention relates to enantiomerically pure compounds of formula (1), wherein the radicals R1, R2, R3, R4and X are defined as in claims and a description. A method for producing said compounds and the use thereof
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Page/Page column 22

(2008/06/13)

Chemical Properties

Boiling Point: 649.05 °C at 760 mmHg
Flash Point:346.333 °C
Density: 1.251 g/cm³
PKA: 9.42±0.20(Predicted)
PSA: 103.54000
LogP: 2.85200

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868049-49-4

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Chemical Properties

Boiling Point: 649.05 °C at 760 mmHg

Flash Point:346.333 °C

Density: 1.251 g/cm³

PKA: 9.42±0.20(Predicted)

PSA: 103.54000

LogP: 2.85200

Global suppliers and manufacturers of 868049-49-4total 68 suppliers on LookChem

Article Database

868049-49-4

Articles about 868049-49-4Total 5 be found

More Articles about upstream products of 868049-49-4

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Chemical Properties

Boiling Point: 649.05 °C at 760 mmHg

Flash Point:346.333 °C

Density: 1.251 g/cm3

PKA: 9.42±0.20(Predicted)

PSA: 103.54000

LogP: 2.85200

Global suppliers and manufacturers of 868049-49-4total 68 suppliers on LookChem

Density: 1.251 g/cm³