- PYRIDINONE DERIVATIVES AS SELECTIVE CYTOTOXIC AGENTS AGAINST HIV INFECTED CELLS
-
The present disclosure is directed to pyridinone derivatives of Formula I and their use for selectively killing HIV infected GAG-POL expressing cells without concomitant cytotoxicity to HIV nave cells, and for the treatment of infection by HIV, or for the treatment, prophylaxis or delay in the onset or progression of AIDS or AIDS Related Complex (ARC).
- -
-
Page/Page column 52
(2020/12/07)
-
- MACROCYCLIC COMPOUNDS AS TRK KINASES INHIBITORS
-
Provided are certain TRK inhibitors, pharmaceutical compositions thereof, and methods of use thereof.
- -
-
Paragraph 145; 190; 191
(2019/10/19)
-
- Compounds and methods for kinase modulation, and indications therefor
-
Compounds and salts thereof, formulations thereof, conjugates thereof, derivatives thereof, forms thereof and uses thereof are described. In certain aspects and embodiments, the described compounds or salts thereof, formulations thereof, conjugates thereo
- -
-
Page/Page column 321; 322
(2015/09/22)
-