34881-45-3Relevant articles and documents
METHOD FOR PRODUCING 1,5-ANHYDRO-1-SUBSTITUTED PHENYL-D-GLUCITOL COMPOUNDS
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Paragraph 0065, (2017/07/25)
PROBLEM TO BE SOLVED: To provide a novel method for producing 1,5-anhydro-1-substituted phenyl-D-glucitol compounds useful as medicines having the action of inhibiting sodium-dependent glucose cotransporters 1. SOLUTION: The present invention provides a method for producing 1,5-anhydro-1-substituted phenyl-D-glucitol compounds represented by formula (XI), wherein, compounds represented by formula (II) are converted through a plurality of steps to produce the compounds represented by formula (XI). SELECTED DRAWING: None COPYRIGHT: (C)2017,JPO&INPIT
METHODS AND COMPOSITIONS FOR TREATING DISEASES AND CONDITIONS
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Paragraph 176; 178, (2016/01/25)
Provided herein include methods and compositions for treating diseases or conditions. In some embodiments provided are methods for treating one or more diseases or conditions selected from the group consisting of hypertension, heart failure, dyspnea, and
SUBSTITUTED DIHYDRO AND TETRAHYDRO OXAZOLOPYRIMIDINONES, PREPARATION AND USE THEREOF
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Page/Page column 50, (2010/04/23)
The present invention relates to a series of substituted dihydro and tetrahydro oxazolopyrimidinones, specifically, to a series of 2-substituted-2,3-dihydro-oxazolo[3,2-a]pyrimidin-7-ones and 2-substituted-2,3,5,6-tetra-hydro-oxazolo[3,2-a]pyrimidin-7-ones of formula (I): Wherein p, n, X, Y, R1, R2, R3, R4, R5, R6, R7 and R8 are as defined herein. This invention also relates to methods of making these compounds including novel intermediates. The compounds of this invention are modulators of metabotropic glutamate receptors (mGluR), particularly, mGluR2 receptor. Therefore, the compounds of this invention are useful as pharmaceutical agents, especially in the treatment and/or prevention of a variety of central nervous system disorders (CNS), including but not limited to acute and chronic neurodegenerative conditions, psychoses, convulsions, anxiety, depression, migraine, pain, sleep disorders and emesis.