53617-35-9 Usage
Description
4-(PIPERIDIN-4-YL)-MORPHOLINE is a heterocyclic compound that consists of a morpholine ring fused with a piperidine moiety. It is a versatile building block in organic synthesis and has a wide range of applications in the pharmaceutical and chemical industries due to its unique structural and functional properties.
Uses
Used in Pharmaceutical Industry:
4-(PIPERIDIN-4-YL)-MORPHOLINE is used as a reactant for the synthesis of selective adenosine A2A receptor antagonists, which are important for the treatment of various neurological disorders, such as Parkinson's disease.
4-(PIPERIDIN-4-YL)-MORPHOLINE is also used as a building block for the development of antidepressant drugs, which help in the treatment of mood disorders, such as major depressive disorder and anxiety.
4-(PIPERIDIN-4-YL)-MORPHOLINE is used as a key intermediate in the synthesis of small molecules that restore E-cadherin expression and reduce invasion in colorectal carcinoma cells, which can help in the development of targeted cancer therapies.
4-(PIPERIDIN-4-YL)-MORPHOLINE is used as a precursor for the development of orally bioavailable P2Y12 antagonists, which are important for the inhibition of platelet aggregation and prevention of thrombotic events.
Used in Chemical Industry:
4-(PIPERIDIN-4-YL)-MORPHOLINE is used as a reactant for the synthesis of quinoline derivatives with antimicrobial activity, which can be employed as effective agents against various bacterial and fungal infections.
4-(PIPERIDIN-4-YL)-MORPHOLINE is also used as a key intermediate in the synthesis of antimalarial drugs, which are crucial for the treatment and prevention of malaria caused by Plasmodium parasites.
Check Digit Verification of cas no
The CAS Registry Mumber 53617-35-9 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 5,3,6,1 and 7 respectively; the second part has 2 digits, 3 and 5 respectively.
Calculate Digit Verification of CAS Registry Number 53617-35:
(7*5)+(6*3)+(5*6)+(4*1)+(3*7)+(2*3)+(1*5)=119
119 % 10 = 9
So 53617-35-9 is a valid CAS Registry Number.
InChI:InChI=1S/C9H18N2O/c1-3-10-4-2-9(1)11-5-7-12-8-6-11/h9-10H,1-8H2
53617-35-9Relevant articles and documents
METHOD FOR PREPARING 4-(PIPERIDIN-4-YL)MORPHOLINE
-
Paragraph 0066-0067, (2019/07/23)
The object of the present invention is to provide a method for preparing 4-(piperidin-4-yl)morpholine, which is easy to operate. The object can be solved by a method for preparing 4-(1-benzylpiperidin-4-yl)morpholine, characterized in that 5-fold molar or more of morpholine is added to 1-benzyl-4-piperidone, and the mixture is reacted with hydrogen under 1 MPa or less in the presence of platinum catalyst or palladium catalyst.
C-3 NOVEL TRITERPENONE WITH C-17 REVERSE AMIDE DERIVATIVES AS HIV INHIBITORS
-
, (2018/03/06)
The present invention relates to C-3 novel triterpenone with C-17 reverse amide compounds of Formula (I); and pharmaceutically acceptable salts thereof, wherein ring Formula (II), R1, R2, R3, R4, R5, R6, R7, 'n' and 'm' are as defined in Formula (I). The invention also relates to C-3 novel triterpenone with C-17 reverse amide derivatives, related compounds, and pharmaceutical compositions useful for the therapeutic treatment of viral diseases and particularly HIV mediated diseases.
Tyrosine Kinase Inhibitor And Uses Thereof
-
, (2017/05/15)
Disclosed is a compound of Formula (I) or a pharmaceutically acceptable salt, ester, or solvate thereof, or their stereoisomers, which can be used as tyrosine kinase inhibitor. Also disclosed is a method for preparing the compound, a pharmaceutical composition and a kit comprising the compound, and uses of the compound. The compound can be used as tyrosine kinase inhibitor, or can be used to reduce or inhibit activity of EGFR or mutant thereof, such as EGFR mutant comprising T790M mutation, in a cell, or to treat and/or prevent a disease associated with overactivity of EGFR, such as cancer.