- Carbenicillin disodium
- Carbenicillin Phenyl
- Carbenicillin phenyl sodium
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Cas Database |
| Name |
Carbenicillin disodium |
EINECS | 225-360-8 |
| CAS No. | 4800-94-6 | Density | N/A |
| PSA | 154.97000 | LogP | -1.85410 |
| Solubility | Soluble in water. | Melting Point |
N/A |
| Formula | C17H16N2Na2O6S | Boiling Point | 737.8 °C at 760 mmHg |
| Molecular Weight | 422.369 | Flash Point | 400 °C |
| Transport Information | UN 1170 3/PG 3 | Appearance | Almost white solid. |
| Safety | 22-36/37-36 | Risk Codes | 42/43 |
| Molecular Structure |
|
Hazard Symbols |
 Xn
|
| Synonyms |
4-Thia-1-azabicyclo[3.2.0]heptane-2-carboxylicacid, 6-[(carboxyphenylacetyl)amino]-3,3-dimethyl-7-oxo-, disodium salt,(2S,5R,6R)- (9CI);4-Thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid,6-[(carboxyphenylacetyl)amino]-3,3-dimethyl-7-oxo-, disodium salt, [2S-(2a,5a,6b)]-;Malonamic acid,N-(2-carboxy-3,3-dimethyl-7-oxo-4-thia-1-azabicyclo[3.2.0]hept-6-yl)-2-phenyl-,disodium salt (7CI,8CI);Anabactyl;BRL 2064;CP 15639-2;Carbapen;Carbecin;Carbenicillin disodium salt;Carbenicillin sodium;Carbenicilline disodium;Carboxybenzylpenicillin sodium;Disodium (a-carboxybenzyl)penicillin;Disodium carbenicillin;Fugacillin;Geopen;Hyoper;Microcillin;Piopen;Pyopen;Sodium carbenicillin;a-Carboxybenzylpenicillin disodiumsalt;a-Carboxybenzylpenicillin sodiumsalt; |
Article Data | 1 |
Carbenicillin disodium Chemical Properties
Product Name: Carbenicillin sodium (CAS NO.4800-94-6)
Molecular Formula: C17H16N2Na2O6S
Molecular Weight: 422.36g/mol
Mol File: 4800-94-6.mol
Einecs: 225-360-8
Appearance: White to off-white powder
Boiling point: 737.8 °C at 760 mmHg
Storage Temperature: 2-8°C
Flash Point: 400 °C
Water Solubility: H2O: 50 mg/mL
Enthalpy of Vaporization: 112.96 kJ/mol
Vapour Pressure: 7.42E-23 mmHg at 25°C
H-Bond Donor: 1
H-Bond Acceptor: 6
Product Categories: Heterocyclic Compounds; Antibiotic Explorer
Carbenicillin disodium Toxicity Data With Reference
Organism Test Type Route Reported Dose (Normalized Dose) Effect Source dog LD50 intravenous > 4gm/kg (4000mg/kg) GASTROINTESTINAL: NAUSEA OR VOMITING Gekkan Yakuji. Pharmaceuticals Monthly. Vol. 11, Pg. 1589, 1969. dog LD50 subcutaneous > 4gm/kg (4000mg/kg) GASTROINTESTINAL: NAUSEA OR VOMITING Gekkan Yakuji. Pharmaceuticals Monthly. Vol. 11, Pg. 1589, 1969. monkey LD50 intravenous 9800mg/kg (9800mg/kg) SENSE ORGANS AND SPECIAL SENSES: PTOSIS: EYE
BEHAVIORAL: MUSCLE CONTRACTION OR SPASTICITY)
LUNGS, THORAX, OR RESPIRATION: DYSPNEATakeda Kenkyusho Ho. Journal of the Takeda Research Laboratories. Vol. 34, Pg. 405, 1975. mouse LD50 intracrebral 95500ug/kg (95.5mg/kg) Chemotherapy Vol. 17, Pg. 1111, 1969. mouse LD50 intraperitoneal 7600mg/kg (7600mg/kg) Drugs in Japan Vol. 6, Pg. 187, 1982. mouse LD50 intravenous 4500mg/kg (4500mg/kg) Chemotherapy Vol. 23, Pg. 572, 1975. mouse LD50 oral > 12gm/kg (12000mg/kg) Chemotherapy Vol. 23, Pg. 572, 1975. mouse LD50 subcutaneous 9gm/kg (9000mg/kg) Drugs in Japan Vol. 6, Pg. 187, 1982. rabbit LD50 intravenous > 4gm/kg (4000mg/kg) SENSE ORGANS AND SPECIAL SENSES: OTHER: EYE Gekkan Yakuji. Pharmaceuticals Monthly. Vol. 11, Pg. 1589, 1969. rabbit LD50 subcutaneous > 4gm/kg (4000mg/kg) SENSE ORGANS AND SPECIAL SENSES: OTHER: EYE Gekkan Yakuji. Pharmaceuticals Monthly. Vol. 11, Pg. 1589, 1969. rat LD50 intraperitoneal 10gm/kg (10000mg/kg) Drugs in Japan Vol. 6, Pg. 187, 1982. rat LD50 intravenous 6800mg/kg (6800mg/kg) Drugs in Japan Vol. 6, Pg. 187, 1982. rat LD50 oral > 10gm/kg (10000mg/kg) Drugs in Japan Vol. 6, Pg. 187, 1982. rat LD50 subcutaneous > 10gm/kg (10000mg/kg) Drugs in Japan Vol. 6, Pg. 187, 1982.
Carbenicillin disodium Safety Profile
Mildly toxic by subcutaneous, intravenous, and intraperitoneal routes. When heated to decomposition it emits very toxic fumes of NOx, Na2O, and SOx. See also CARBENICILLIN PHENYL SODIUM.
Safety Information of Carbenicillin sodium (CAS NO.4800-94-6):
Hazard Codes: Xn.gif){kind=small}
Risk Statements: 42/43
42: May cause sensitization by inhalation
43: May cause sensitization by skin contact
Safety Statements: 22-36/37-36
22: Do not breathe dust
36: Wear suitable protective clothing
37: Wear suitable gloves
Carbenicillin disodium Specification
Carbenicillin sodium ,its CAS NO. is 4800-94-6,the synonyms is Brl-2064 ; Carbecin ; Carboxybenzylpenicillinsodium ; Cp-15-639-2 ; Disodiumcarbenicillin ; Fugacillin ; Geopen ; Gripenin .
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