- Barbier(-type) Reaction
-
Barbier(-type) Reaction
P. Barbier, C. R. Acad. Sci. 128, 110 (1899).
One-step procedure for the preparation of alcohols from organic halides and aldehydes or ketones:
Review of mechanistic studies of Sm-mediated coupling: D. P. Curran et al., Synlett 1992, 943-961. Book: C. Blomberg, The Barbier Reaction and Related One-Step Processes, K. Hafner et al., Eds. (Springer-Verlag, New York, 1993) 183 pp. Zn-promoted coupling: F. Hong et al., Chem. Commun. 1994, 289. Sm-mediated coupling: M. Kunishima et al., Chem. Pharm. Bull. 42, 2190 (1994). Comparison with Ni(0) insertion chemistry for intramolecular cyclization: M. Kihara et al., Tetrahedron 48, 67 (1992). Cf. Grignard Reaction.
Prev: Barbier-Wieland Degradation
Next: Bamford-Stevens Reaction - 【Back】【Close 】【Print】【Add to favorite 】
- Related information
- Reaction routes of Metronidazole
- Reaction Kettle_008
- Production of 4-(2-Bromo-2-propenyl)-4-methyl-γ-butyrolactone by the Reaction of Ethyl levulinate with (2-bromoallyl)diisopropoxyborane
- Double Hydroxylation Reaction: 16α-Methylcortexolone
- Diels-Alder reaction: (1S-endo)-3-(Bicyclo[2.2.1]hept-5-en-2-ylcarbonyl)-2-oxazolidinone
- 4-(2-Bromo-2-propenyl)-4-methyl-gamma-butyrolactone: from the reaction of Ethyl levulinate and (2-Bromoallyl)diisopropoxyborane
- Synthesis of trans-4,4'-Dibromostilbene by a Double Heck Reaction of (Arylazo)amines with Vinyltriethoxysilane
- Single Displacement Reactions
- Reaction Design
- Chemical Reaction Stoichiometry (CRS, Tutorial, Java Applet, and Resources)
-
Health and Chemical more >
-
Hot Products
- 12112-67-3 Chloro(1,5-cyclooctadiene)iridium(I) dimer
- 128-39-2 Phenol,2,6-bis(1,1-dimethylethyl)-
- 832681-49-9 {4-[(Cyclopropylcarbonyl)amino]phenyl}acetic acid
- 373-57-9 Trifluoro(methanol)boron
- 11042-64-1 gamma-Oryzanol
- 112022-81-8 (S)-3,3-Diphenyl-1-methylpyrrolidino[1,2-c]-1,3,2-oxazaborole
- 10026-22-9 Cobaltous nitrate hexahydrate
- 1393-62-0 Abrins
- 192704-56-6 Pregn-4-ene-7,21-dicarboxylicacid, 11,17-dihydroxy-3-oxo-, g-lactone, methyl ester, (7a,11a,17a)-
- 69-79-4 Maltose
- 925-83-7 Sebacic dihydrazide
- 482-89-3 Indigo