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DL-Ephedrine hydrochloride

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Name

DL-Ephedrine hydrochloride

EINECS 200-074-6
CAS No. 134-71-4 Density N/A
PSA 32.26000 LogP 2.52080
Solubility 250g/L at 20℃ Melting Point 216-220 °C(lit.)
Formula C10H15 N O . Cl H Boiling Point 255 °C at 760 mmHg
Molecular Weight 201.696 Flash Point 85.6 °C
Transport Information N/A Appearance White solid
Safety 26-36 Risk Codes 22-36/37/38
Molecular Structure Molecular Structure of 134-71-4 (DL-Ephedrine hydrochloride) Hazard Symbols HarmfulXn
Synonyms

Benzenemethanol,a-[(1R)-1-(methylamino)ethyl]-,hydrochloride, (aS)-rel-(9CI);Benzenemethanol, a-[1-(methylamino)ethyl]-,hydrochloride, (R*,S*)-;Ephetonin;Ephetonine;Racephedrine Hydrochloride;dl-Ephedrinehydrochloride;

 

DL-Ephedrine hydrochloride Chemical Properties

IUPAC Name: 2-(Methylamino)-1-phenylpropan-1-ol hydrochloride
The MF of DL-Ephedrine hydrochloride (CAS NO.134-71-4) is C10H16ClNO.

                                   
The MW of DL-Ephedrine hydrochloride (CAS NO.134-71-4) is 201.69.
Synonyms of DL-Ephedrine hydrochloride (CAS NO.134-71-4): (1R)-2-(Methylamino)-1-phenylpropan-1-ol hydrochloride ; Benzenemethanol, alpha-[1-(methylamino)ethyl]-, (alphaR)-, hydrochloride ; Ephedrine hydrochloride
Flash Point: 130.2 °C
Boiling Point: 291.7 °C
Melting Point: 16-20 °C
Merck: 13,3639

DL-Ephedrine hydrochloride Uses

    DL-Ephedrine hydrochloride (CAS NO.134-71-4) is used for the prevention of bronchial asthma and relieve mild asthma.

DL-Ephedrine hydrochloride Toxicity Data With Reference

1.    

orl-wmn TDLo:1 mg/kg:CAR,GIT,SKN

    JPETAB    Journal of Pharmacology and Experimental Therapeutics. 33 (1928),237.
2.    

orl-man TDLo:1429 µg/kg

    JPETAB    Journal of Pharmacology and Experimental Therapeutics. 33 (1928),237.
3.    

scu-rat LD50:350 mg/kg

    AEPPAE    Naunyn-Schmiedeberg’s Archiv fuer Experimentelle Pathologie und Pharmakologie. 169 (1933),114.
4.    

orl-mus LD50:700 mg/kg

    JMCMAR    Journal of Medicinal Chemistry. 9 (1966),966.
5.    

ipr-mus LD50:254 mg/kg

    PHARAT    Pharmazie. 24 (1969),775.
6.    

scu-mus LD50:520 mg/kg

    NYKZAU    Nippon Yakurigaku Zasshi. Japanese Journal of Pharmacology. 55 (1959),653.
7.    

ivn-mus LD50:135 mg/kg

    JMCMAR    Journal of Medicinal Chemistry. 9 (1966),966.
8.    

ivn-rbt LDLo:60 mg/kg

    JPETAB    Journal of Pharmacology and Experimental Therapeutics. 36 (1929),363.

DL-Ephedrine hydrochloride Consensus Reports

Reported in EPA TSCA Inventory.

DL-Ephedrine hydrochloride Safety Profile

Poison by subcutaneous, intravenous, and intraperitoneal routes. Moderately toxic by ingestion. Human systemic effects: cardiac changes, nausea or vomiting, sweating. When heated to decomposition it emits very toxic fumes of HCl and NOx. See also EPHEDRINE.Safety information of DL-Ephedrine hydrochloride (CAS NO.134-71-4):
Hazard Codes  HarmfulXn
Risk Statements  22-36/37/38 
R22:Harmful if swallowed. 
R36/37/38:Irritating to eyes, respiratory system and skin.
Safety Statements  26-36
S26: In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. 
S36:Wear suitable protective clothing.
RIDADR  1544
WGK Germany  3
RTECS  KB1750000
HazardClass  6.1(b)
PackingGroup  III