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Dexbrompheniramine maleate

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Dexbrompheniramine maleate

EINECS N/A
CAS No. 2391-03-9 Density g/cm3
PSA 90.73000 LogP 3.63950
Solubility N/A Melting Point 132-134℃
Formula C16H19BrN2•C4H4O4 Boiling Point 403°Cat760mmHg
Molecular Weight 435.36 Flash Point 197.5°C
Transport Information N/A Appearance N/A
Safety Poison by ingestion, intramuscular and intraperitoneal routes. When heated to decomposition it emits toxic fumes of Br and NOx. Risk Codes 25
Molecular Structure Molecular Structure of 2391-03-9 (DEXBROMPHENIRAMINE MALEATE) Hazard Symbols
Synonyms

(+)-2-(p-bromo-alpha-(2-(dimethylamino)ethyl)benzyl)pyridinemaleate;d-brompheniraminemaleate;disomermaleate;gamma-(4-bromophenyl)-n,n-dimethyl-2-pyridinepropanamin(s)-2-pyridinepropanamin(z)-2-buten;pyridine,2-(p-bromo-alpha-(2-(dimethylamino)ethyl)benzyl)-,maleate(1:1),(s);(+)-BROMPHENIRAMINE MALEATE SALT;DEXBROMPHENIRAMINE MALEATE;DEXBROMPHENIRAMINE MALEATE SALT

Article Data 2

Dexbrompheniramine maleate Chemical Properties

Empirical Formula: C20H23BrN2O4
Molecular Weight: 435.3116 g/mol
EINECS: 219-236-2 
Flash Point: 197.5 °C
Enthalpy of Vaporization: 65.42 kJ/mol
Boiling Point: 403 °C at 760 mmHg
Vapour Pressure: 1.05E-06 mmHg at 25 °C
Structure of Dexbrompheniramine maleate (CAS NO.2391-03-9):
    
IUPAC Name of Dexbrompheniramine maleate (CAS NO.2391-03-9): (3S)-3-(4-Bromophenyl)-N,N-dimethyl-3-pyridin-2-ylpropan-1-amine ; (Z)-But-2-enedioic acid

Dexbrompheniramine maleate Toxicity Data With Reference

Organism Test Type Route Reported Dose (Normalized Dose) Effect Source
guinea pig LD50 oral 259mg/kg (259mg/kg) SENSE ORGANS AND SPECIAL SENSES: MYDRIASIS (PUPILLARY DILATION): EYE
BEHAVIORAL: TREMOR
BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD
Chemotherapia. Vol. 3, Pg. 120, 1961.
mouse LD50 intraperitoneal 106mg/kg (106mg/kg) SENSE ORGANS AND SPECIAL SENSES: MYDRIASIS (PUPILLARY DILATION): EYE
BEHAVIORAL: TREMOR
BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD
Chemotherapia. Vol. 3, Pg. 120, 1961.
mouse LD50 intravenous 25mg/kg (25mg/kg) SENSE ORGANS AND SPECIAL SENSES: MYDRIASIS (PUPILLARY DILATION): EYE
BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD
BEHAVIORAL: TREMOR
Chemotherapia. Vol. 3, Pg. 120, 1961.
mouse LD50 oral 176mg/kg (176mg/kg) SENSE ORGANS AND SPECIAL SENSES: MYDRIASIS (PUPILLARY DILATION): EYE
BEHAVIORAL: TREMOR
BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD
Chemotherapia. Vol. 3, Pg. 120, 1961.
rat LD50 intraperitoneal 104mg/kg (104mg/kg) SENSE ORGANS AND SPECIAL SENSES: MYDRIASIS (PUPILLARY DILATION): EYE
BEHAVIORAL: TREMOR
BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD
Chemotherapia. Vol. 3, Pg. 120, 1961.
rat LD50 oral 191mg/kg (191mg/kg) SENSE ORGANS AND SPECIAL SENSES: MYDRIASIS (PUPILLARY DILATION): EYE
BEHAVIORAL: TREMOR
BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD
Chemotherapia. Vol. 3, Pg. 120, 1961.
 

Dexbrompheniramine maleate Safety Profile

Hazard Codes of Dexbrompheniramine maleate (CAS NO.2391-03-9): ToxicT
Risk Statements: 25 
R25 :Toxic if swallowed.
Safety Statements: 22-36/37/39-45 
S22:Do not breathe dust. 
S36/37/39:Wear suitable protective clothing, gloves and eye/face protection. 
S45:In case of accident or if you feel unwell, seek medical advice immediately (show the label whenever possible.)

Dexbrompheniramine maleate Specification

 Dexbrompheniramine maleate ,its cas register number is 2391-03-9. It also can be called Brompheniramine d-form maleate ; Dimetane ;and Pyridine, 2-(p-bromo-alpha-(2-(dimethylamino)ethyl)benzyl)-, maleate (1:1), (S)- .

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