- Ergonovine
- Ergonovine maleate
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| Name |
Ergonovine maleate |
EINECS | 204-953-5 |
| CAS No. | 129-51-1 | Density | 1.3g/cm3 |
| PSA | 142.96000 | LogP | 1.57520 |
| Solubility | Sparingly soluble in water and ethanol (~750 g/l) TS; practically insoluble in ether R | Melting Point |
ca. 200 C |
| Formula | C19H23N3O2.C4H4O4 | Boiling Point | 635.2 ºCat 760 mmHg |
| Molecular Weight | 441.484 | Flash Point | 337.9 ºC |
| Transport Information | UN 1544 6 | Appearance | white or faintly yellow, crystalline powder; odourless. |
| Safety | 36/37-45 | Risk Codes | 23/24/25 |
| Molecular Structure |
|
Hazard Symbols |
 T
|
| Synonyms |
Metriclavin;Ergonovine, maleate (1:1);Ergotrate Maleate;Ergomet;Cornocentin;Ergometrine maleate (JP14);Ergotrate;Ergometrine (TN);D-Ergonovine maleate;Ergonovine maleate (USP);Ermetrin;Ergonovine maleate (TN);Ergoline-8-.beta.-carboxamide, 9, 10-didehydro-N- ((S)-2-hydroxy-1-methylethyl)-6-methyl-, maleate (1:1) (salt);Ergometrine acid maleate;Ergotrate maleate (TN);Ergometrin maleate;Ergoline-8.beta.-carboxamide, 9,10-didehydro-N- ((S)-2-hydroxy-1-methylethyl)-6-methyl-, maleate (1:1) (salt);Ergoline-8-carboxamide, 9, 10-didehydro-N- (2-hydroxy-1-methylethyl)-6-methyl-, [8.beta.(S)]-, (Z)-2-butenedioate (1:1) (salt);Ergonovine, maleate (1:1) (salt);Ergoline-8-carboxamide,9,10-didehydro-N- [(1S)-2-hydroxy-1-methylethyl]-6-methyl-,(8a)-,(2Z)-2-butenedioate (1:1) (salt);Oxytocic;Ergometrine maleate (1:1);Ergot;Ergometrine;Ergometrine maleate;ERGOT;ERGONO-VINE, MALEATE (1:1) (SALT);CRUDE ERGOT; |
Ergonovine maleate Specification
Ergonovine maleate (CAS NO.129-51-1) is used in chemical reagents, organic intermediates, fine chemicals, pharmaceutical research and development.
A deadly human poison. Experimental poison by intravenous route. Experimental reproductive effects. Human systemic effects: hypermotility, diarrhea, cyanosis, thirst, tachycardia, confusion, coma, central nervous system symptoms, gangrene; circulatory changes can follow ingestion. Questionable carcinogen with experimental tumorigenic data. Mutation data reported. When heated to decomposition it emits toxic fumes of NOx. See also individual components. Ergonovine maleate (CAS NO.129-51-1) is one kind of dangerous material, because it has toxic by inhalation, in contact with skin and if swallowed, In case of accident or if you feel unwell, seek medical advice immediately (show label where possible). And its toxicity is:
| Organism | Test Type | Route | Reported Dose (Normalized Dose) | Effect | Source |
|---|---|---|---|---|---|
| guinea pig | LDLo | intravenous | 80mg/kg (80mg/kg) | BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD SKIN AND APPENDAGES (SKIN): HAIR: OTHER | Journal of Pharmacology and Experimental Therapeutics. Vol. 54, Pg. 398, 1935. |
| infant | TDLo | intramuscular | 40ug/kg (0.04mg/kg) | GASTROINTESTINAL: "HYPERMOTILITY, DIARRHEA" LUNGS, THORAX, OR RESPIRATION: CYANOSIS | JAMA, Journal of the American Medical Association. Vol. 250, Pg. 729, 1983. |
| man | LDLo | unreported | 15mg/kg (15mg/kg) | "Poisoning; Toxicology, Symptoms, Treatments," 2nd ed., Arena, J.M., Springfield, IL, C.C. Thomas, 1970Vol. 2, Pg. 73, 1970. | |
| mouse | LD50 | intravenous | 8260ug/kg (8.26mg/kg) | Toxicology and Applied Pharmacology. Vol. 23, Pg. 537, 1972. |
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