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Fenoprofen sodium

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Name

Fenoprofen sodium

EINECS N/A
CAS No. 34691-31-1 Density N/A
PSA N/A LogP N/A
Solubility N/A Melting Point N/A
Formula C15H13O3•Na Boiling Point 381.3°C at 760 mmHg
Molecular Weight 264.27 Flash Point 141.7°C
Transport Information N/A Appearance N/A
Safety Poison by intraperitoneal route. Moderately toxic by ingestion, subcutaneous, and intravenous routes. When heated to decomposition it emits toxic fumes of Na2O. See also FENOPROFEN CALCIUM DIHYDRATE. Risk Codes N/A
Molecular Structure Molecular Structure of 34691-31-1 (sodium 2-(3-phenoxyphenyl)propanoate) Hazard Symbols N/A
Synonyms

N/A

 

Fenoprofen sodium Chemical Properties

IUPAC Name: Sodium 2-(3-phenoxyphenyl)propanoate
Synonyms of Fenoprofen sodium (CAS NO.34691-31-1): D,l-2-(3-Phenoxyphenyl)propionic acid, sodium salt ; Propionic acid, 2-(3-phenoxyphenyl)-, sodium salt, (+-)-
InChI: InChI=1/C15H14O3.Na/c1-11(15(16)17)12-6-5-9-14(10-12)18-13-7-3-2-4-8-13;/h2-11H,1H3,(H,16,17);/q;+1/p-1
CAS NO: 34691-31-1
Molecular Formula: C15H13NaO3
Molecular Weight : 264.2517
Molecular Structure:
H bond acceptors: 3
H bond donors: 1
Freely Rotating Bonds: 4
Polar Surface Area: 46.53 Å2
Flash Point: 141.7 °C
Enthalpy of Vaporization: 66.41 kJ/mol
Boiling Point: 381.3 °C at 760 mmHg
Vapour Pressure: 1.71E-06 mmHg at 25°C

Fenoprofen sodium Toxicity Data With Reference

Organism Test Type Route Reported Dose (Normalized Dose) Effect Source
dog LD intravenous > 100mg/kg (100mg/kg)   Pharmacological and Biochemical Properties of Drug Substances. Vol. 1, Pg. 183, 1977.
dog LD oral > 200mg/kg (200mg/kg)   Pharmacological and Biochemical Properties of Drug Substances. Vol. 1, Pg. 183, 1977.
mouse LD50 intraperitoneal 286mg/kg (286mg/kg) GASTROINTESTINAL: PERITONITIS Kiso to Rinsho. Clinical Report. Vol. 14, Pg. 4385, 1980.
mouse LD50 intravenous 471mg/kg (471mg/kg) BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD

LUNGS, THORAX, OR RESPIRATION: RESPIRATORY DEPRESSION

BEHAVIORAL: ATAXIA
Kiso to Rinsho. Clinical Report. Vol. 14, Pg. 4385, 1980.
mouse LD50 subcutaneous 463mg/kg (463mg/kg) BEHAVIORAL: SOMNOLENCE (GENERAL DEPRESSED ACTIVITY) Kiso to Rinsho. Clinical Report. Vol. 14, Pg. 4385, 1980.
rat LD50 intraperitoneal 234mg/kg (234mg/kg) GASTROINTESTINAL: OTHER CHANGES Kiso to Rinsho. Clinical Report. Vol. 14, Pg. 4385, 1980.
rat LD50 intravenous 500mg/kg (500mg/kg) BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD

LUNGS, THORAX, OR RESPIRATION: RESPIRATORY DEPRESSION
Toxicology and Applied Pharmacology. Vol. 25, Pg. 444, 1973.
rat LD50 oral 800mg/kg (800mg/kg) BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD

LUNGS, THORAX, OR RESPIRATION: RESPIRATORY DEPRESSION
Toxicology and Applied Pharmacology. Vol. 25, Pg. 444, 1973.
rat LD50 subcutaneous 500mg/kg (500mg/kg) BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD

LUNGS, THORAX, OR RESPIRATION: RESPIRATORY DEPRESSION
Toxicology and Applied Pharmacology. Vol. 25, Pg. 444, 1973.

Fenoprofen sodium Safety Profile

Poison by intraperitoneal route. Moderately toxic by ingestion, subcutaneous, and intravenous routes. When Fenoprofen sodium (CAS NO.34691-31-1) is heated to decomposition, it emits toxic fumes of Na2O. See also FENOPROFEN CALCIUM DIHYDRATE.

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