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Food green 3

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Name

Food green 3

EINECS 219-091-5
CAS No. 2353-45-9 Density 0.513[at 20℃]
PSA 223.22000 LogP 7.97490
Solubility Soluble in water, glycerin, glycol and ethanol. Melting Point 290 °C (dec.)(lit.)
Formula C37H34N2Na2O10S3 Boiling Point 260℃[at 101 325 Pa]
Molecular Weight 808.862 Flash Point N/A
Transport Information N/A Appearance green powder
Safety 22-24/25-37/39-25 Risk Codes 68-40-20/21/22
Molecular Structure Molecular Structure of 2353-45-9 (Food green 3) Hazard Symbols HarmfulXn
Synonyms

Benzenemethanaminium,N-ethyl-N-[4-[[4-[ethyl[(3-sulfophenyl)methyl]amino]phenyl](4-hydroxy-2-sulfophenyl)methylene]-2,5-cyclohexadien-1-ylidene]-3-sulfo-,hydroxide, inner salt, disodium salt;Benzenemethanaminium, N-ethyl-N-[4-[[4-[ethyl[(3-sulfophenyl)methyl]amino]phenyl](4-hydroxy-2-sulfophenyl)methylene]-2,5-cyclohexadien-1-ylidene]-3-sulfo-,inner salt, disodium salt (9CI);C.I. Food Green 3 (7CI);C.I. Food Green 3,disodium salt (8CI);Fast Green FCF (6CI);C.I. 42053;FD and C Green No. 3;C Green No. 3;FDC Green 3;Food Green No. 3;Green No. 3;Japan Food Green No. 3;Japan Green 3;Japan Green No. 3;NSC379443;

 

Food green 3 Chemical Properties


IUPAC Name: Disodium 2-[[4-[ethyl-[(3-sulfonatophenyl)methyl]amino]phenyl]-[4-[ethyl-[(3-sulfonatophenyl)methyl]azaniumylidene]cyclohexa-2,
5-dien-1-ylidene]methyl]-5-hydroxybenzenesulfonate  
Canonical SMILES: CCN(CC1=CC(=CC=C1)S(=O)(=O)[O-])C2=CC=C(C=C2)C(=C3C=CC(=[N+](CC)CC4=CC(=CC=C4)S(=O)(=O)[O-])C=C3)C5=C(C=C(C=C5)O)S(=O)(=O)[O-].[Na+].[Na+]
InChI: InChI=1S/C37H36N2O10S3.2Na/c1-3-38(24-26-7-5-9-33(21-26)50(41,42)43)30-15-11-28(12-16-30)37(35-20-19-32(40)23-36(35)52(47,
48)49)29-13-17-31(18-14-29)39(4-2)25-27-8-6-10-34(22-27)51(44,45)46;;/h5-23H,3-4,24-25H2,1-2H3,(H3,41,42,43,44,45,46,47,48,49);;/q;2*+1/p-2
Empirical Formula: C37H34N2Na2O10S3
Molecular Weight: 808.8478 
EINECS: 228-058-4 
Melting point: 290 °C (dec.)(lit.)
Storage temp.: Store at RT.
Colour Index: 42053
Sensitive: Hygroscopic
Appearance: Green powder
Classification Code: Mutation data; Tumor data
Product categories of Food green 3 (CAS.2353-45-9): Organics;Analytical Chemistry;Food Colors by Food Sanitation Law in Japan

Food green 3 Toxicity Data With Reference

Organism Test Type Route Reported Dose (Normalized Dose) Effect Source
rat LD50 oral > 2gm/kg (2000mg/kg)   Merck Index. Vol. 11, Pg. 618, 1989.

Food green 3 Consensus Reports

IARC Cancer Review: Group 3 IMEMDT    IARC Monographs on the Evaluation of Carcinogenic Risk of Chemicals to Man . 7 (1987),p. 56.(World Health Organization, Internation Agency for Research on Cancer,Lyon, France.: ) (Single copies can be ordered from WHO Publications Centre U.S.A., 49 Sheridan Avenue, Albany, NY 12210) ; Animal Sufficient Evidence IMEMDT    IARC Monographs on the Evaluation of Carcinogenic Risk of Chemicals to Man . 16 (1978),p. 187.(World Health Organization, Internation Agency for Research on Cancer,Lyon, France.: ) (Single copies can be ordered from WHO Publications Centre U.S.A., 49 Sheridan Avenue, Albany, NY 12210) . Reported in EPA TSCA Inventory. EPA Genetic Toxicology Program.

Food green 3 Safety Profile

Questionable carcinogen with experimental neoplastigenic data. Mutation data reported. When heated to decomposition it emits very toxic fumes of NOx and SOx.
Hazard Codes: HarmfulXn
Risk Statements: 68-40-20/21/22 
R20/21/22:Harmful by inhalation, in contact with skin and if swallowed. 
R40:Limited evidence of a carcinogenic effect. 
R68:Possible risk of irreversible effects.
Safety Statements: 22-24/25-37/39-25 
S22:Do not breathe dust. 
S24/25:Avoid contact with skin and eyes. 
S25:Avoid contact with eyes. 
S37/39:Wear suitable gloves and eye/face protection. 

Food green 3 Specification

 Food green 3 (CAS.2353-45-9) also can be called C.I. 42053 ; Fast Green FCF ; N-Ethyl-N-[4-[[4-[ethyl[(3-sulfophenyl)methyl]amino]phenyl](4-hydroxy-2-sulfophenyl)methylene]-2,5-cyclohexadien-1-ylidene]-3-sulfo-benzenemethanaminium hydroxide inner salt disodium salt ; and; Disodium 2-[(E)-{4-[ethyl(3-sulfonatobenzyl)amino]phenyl}{(4E)-4-[ethyl(3-sulfonatobenzyl)iminio]-2,5-cyclohexadien-1-ylidene}methyl]-5-hydroxybenzenesulfonate .It is hazardous,so the first aid measures and others should be known.Such as: When on the skin: first,should  flush skin with plenty of water immediatelyfor at least 15 minutes while removing contaminated clothing. Secondly,Get shoesmedical aid . Or in the eyes: Flush eyes with plenty of water for at least 15 minutes, occasionally lifting the upper and lower eyelids.Then get medical aid soon.While ,it's Inhaled: Remove from exposure and move to fresh air immediately.Give artificial respiration while not breathing. When breathing is difficult, give oxygen. And as soon as to get medical aid. Then you have the ingesting of the product : Wash mouth out with water,and get medical aid immediately.Notes to physician: Treat supportively and symptomatically.
In addition, Food green 3 (CAS.2353-45-9) can be stable under normal temperature and pressure conditions.It is not compatible with strong oxidizing agents, and you must not take it with incompatible materials. And also prevent it to broken down into hazardous decomposition products: ntrogen oxides, carbon monoxide, oxides of sulfur, carbon dioxide, nitrogen.

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