Journal of Fluorine Chemistry p. 151 - 162 (1982)
Update date:2022-07-29
Topics:
Burmakov, A. I.
Motnyak, L. A.
Kunshenko, B. V.
Alexeeva, L. A.
Yagupolskii L. M.
Treatment of dimethyl (+)-L-tartrate (I) with sulfur tetrafluoride results in the formation of an intermediate, 2-fluoro-1,2-bis(methoxycarbonyl)ethyl fluorosulfite (II), which under the action of hydrogen fluoride, present in the reaction mixture, is converted into dimethyl (-)(2S:3S)-2-fluoro-3-hydroxysuccinate (III).The reaction of the latter with SF4 leads to dimethyl meso-2,3-difluorosuccinate (IV).The structure and configurations of the compounds obtained were established by 1H and 19F NMR.Treatment of dimethyl (+)-L-tartrate (I) with sulfur tetrafluoride in the presence of excessive hydrogen fluoride gave dimethyl meso-2,3-difluorosuccinate in 96percent yield.
View MoreZibo Fuxi'er Chemical Co.,Ltd (Shanxian Fuxi'er Chemical Co.,Ltd)
Contact:+86-533-2091422
Address:Eastern 4 on the 3th Road ,Liangxiang Industrial Park, Zibo city ,Shandong,China
JiangXi Hong Run Chemical Co., Ltd
Contact:+86-0791-88521351
Address:XingHuo industrial zone in YongXiu county
TIANJIN ZHONGXIN CHEMTECH CO.,LTD.
Contact:86-022-89880739
Address:10B, Pan China International Center, No. 931 YingKou Road, TangGu, Tianjin, China, 300451
Jiangsu Willing Bio-Tech Co ltd
website:http://www.willingbio.com/
Contact:+86 18796909136
Address:No 18 Guoqiao Road
JIAXING SUNS INTERNATIONAL TRADE CO LTD
Contact:18367306858
Address:No.123,Huixin Avenue,Huimin Dist
Doi:10.1016/j.jorganchem.2005.11.047
(2006)Doi:10.1039/b006765m
(2000)Doi:10.1021/ic060171q
(2006)Doi:10.1007/BF01150724
(1983)Doi:10.1016/S0040-4039(01)93789-X
(1989)Doi:10.1016/j.poly.2014.05.055
(2014)