Chemistry of Natural Compounds p. 706 - 709 (1986)
Update date:2022-08-05
Topics:
Krysin, E. P.
Karel'skii, V. N.
Rabinovich, A. K.
Borovkova, S. Yu.
A scheme is given for the synthesis of a heptapeptide representing a modified ACTH 4-10 fragment on the basis of which it is possible to create a preparation that is an effective adaptogen of peptide nature.A proposed variant of the synthesis permits a peptide with an adequate degree of purity to be obtained comparatively simply on a large scale.The intermediate compunds and the final products were obtained with good yields and were distinguished by chromatographic homogeneity.The heptapeptide synthesized did not differ with respect to its physicochemical characteristics and biological action from the analogous compound obtained previously.Some physicochemical characteristics of the compound obtained (angles of optical rotation, chromatographic mobilities) are given.
View MoreAntaeus Bio-technology Co., LTD
Contact:021-31252569
Address:shanghai pudong
Shanghai birch chemical technology co.,ltd
Contact:+86-21-54096810
Address:No.2588,Jungong Road,Shanghai,China
Hangzhou Reb Technology Co., Ltd.
Contact:571-81902596
Address:Room 502,Buil.5,No.1 Xi Yuan Rd. The West Lake Science&Technology Park, Hangzhou,Zhejiang,China.
MedicalChem(Yancheng)Manuf.Co.,Ltd.
Contact:+86-515-84383366
Address:Touzeng BinHai, YanCheng City, JiangSu Province, China
website:http://www.sjzthld.com
Contact:86-311-66699812
Address:NO.600 ZHONGSHAN EAST ROAD SHIJIAZHUANG
Doi:10.3184/030823408X282659
(2008)Doi:10.1007/BF00921511
()Doi:10.1016/S0040-4039(01)93759-1
(1989)Doi:10.1021/jo00245a040
(1988)Doi:10.1021/om00093a020
(1988)Doi:10.1007/BF00955860
(1987)