Tetrahedron Letters p. 6845 - 6848 (1993)
Update date:2022-09-26
Topics:
Chen
Wei
Vyas
Doyle
Farina
7,10-Dideoxy taxol 2 was prepared from baccatin III in 4 steps via the Barton deoxygenation reaction. Similarly, 7-epi-10-deoxy taxol 3 was prepared in one step from 7-epi taxol in high yield. The key reaction was the tributyltin hydride-mediated directed reduction of the C10 acetate.
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Doi:10.1080/00397911.2013.815214
(2014)Doi:10.1002/prac.19953370114
(1995)Doi:10.1016/j.bmc.2013.11.043
(2014)Doi:10.1039/P19930002017
(1993)Doi:10.1016/0022-328X(93)80293-K
(1993)Doi:10.1039/c39930001269
(1993)