150930-82-8Relevant articles and documents
A facile synthesis of 7,10-dideoxy taxol and 7-epi-10-deoxy taxol
Chen,Wei,Vyas,Doyle,Farina
, p. 6845 - 6848 (1993)
7,10-Dideoxy taxol 2 was prepared from baccatin III in 4 steps via the Barton deoxygenation reaction. Similarly, 7-epi-10-deoxy taxol 3 was prepared in one step from 7-epi taxol in high yield. The key reaction was the tributyltin hydride-mediated directed reduction of the C10 acetate.
C2 substituted phenyl taxane derivatives and pharmaceutical compositions containing them
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Page column 25, (2010/01/30)
Taxane derivatives having alternative C2 substituents.
Studies on the photochemistry of taxol
Chen,Farina,Huang,Gao,Golik,Doyle
, p. 8633 - 8650 (2007/10/02)
Irradiation of taxol at 280 nm in a Rayonet reactor yielded a novel pentacyclic derivative containing a new bond between C-3 and C-11. The proposed mechanism involves a triplet intermediate and the first event of the oxa-di-π-methane rearrangement. Taxane