Chemistry of Natural Compounds p. 703 - 708 (1982)
Update date:2022-08-03
Topics: Oligonucleotides Nucleotidopeptides XLII Efficacy of the intramolecular influence of the carboxy groups of amino acids As a function of their positions
Yuodka, B. A.
Lioranchaite, L. E.
Baltenas, V. R.
It has been established that remote carboxy groups in nucleotidyl-(5'-->N)-β-alanine and -alanylalanine do not affect the mechanism of the cleavage of the phosphoramide center.The situation is different in the case of nucleotidyl-(5'-->Nε)-lysine.It has been shown that in the 3'-phenylalanine derivative of dTMP, the influence of the α-carboxy group of the amino acid is only half as great as in the 5'-analog.The α-carboxy groups of the amino acids in oligonucleotidyl-(Pin-->N)-amino acids also weaken the mechanism of the cleavage of the phosphoramide centers.
View MoreNantong LiKai Chemical Co.,Ltd
Contact:+86-513-89068669
Address:Jincheng Science Park
HANGZHOU ZHONGCHANG SCIENTIFIC CO.,LTD
Contact:+86-571-88932183
Address:Hangzhou
Beijing Green Guardee Technology CO,.LTD
Contact:+86-10-69706062
Address:F2 BLdj,5 No.37 Chaoqian Road
Nantong Auxin Electronic Technology Co., LTD
Contact:86-513-88760026
Address:NO.5-1, Aoxin Road, Haian Hi-tech Development Zone, Jiangsu Province, China
Weifang Yukai Chemical Co.,Ltd.
website:http://www.yukaichem.com/en.html
Contact:+86-536-8865336
Address:binhai economic development zone,262737 shangdong,china
Doi:10.1016/j.bmcl.2013.09.052
(2013)Doi:10.1016/j.tetlet.2004.01.089
(2004)Doi:10.1016/S0040-4039(01)86725-3
(1979)Doi:10.1055/s-2004-815427
(2004)Doi:10.3987/COM-03-S52
(2003)Doi:10.1002/jhet.5570410112
(2004)