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Acknowledgements
Q.; Doherty, G. A.; Magriotis, P. A.; de Laszlo, S. E.; Li,
B.; MacCoss, M.; Kidambi, U.; Egger, L. A.; McCauley,
E.; Riper, G. V.; Mumford, R. A.; Schmidt, J. A.;
Hagmann, W. K. Bioorg. Med. Chem. Lett. 2002, 12,
1497–1500; (e) Porter, J. R.; Archibald, S. C.; Brown, J.
A.; Childs, K.; Critchley, D.; Head, J. C.; Hutchinson, B.;
Linsley, J. M.; Parton, T. A. H.; Robinson, M. K.; Shock,
A.; Warrellow, G. J.; Zomaya, A. Bioorg. Med. Chem.
Lett. 2002, 12, 1591–1594; (f) Chen, L.; Trilles, R.;
Miklowski, D.; Huang, T.-N.; Fry, D.; Campbell, R.;
Rowan, K.; Schwinge, V.; Tilley, J. W. Bioorg. Med.
Chem. Lett. 2002, 12, 1679–1682; (g) Sidduri, A.; Tilley, J.
W.; Lou, J. P.; Chen, L.; Kaplan, G.; Campbell, R.;
Guthrie, R.; Huang, T.-N.; Rowan, K.; Schwinge, V.;
Renzetti, L. M. Bioorg. Med. Chem. Lett. 2002, 12, 2479–
2482; (h) Doherty, G. A.; Yang, G. X.; Borges, E.; Tong,
S.; McCauley, E. D.; Treonz, K. M.; Riper, G. V.;
Pacholok, S.; Si, Q.; Koo, G. C.; Shah, K.; Mumford, R.
A.; Hagmann, W. K. Bioorg. Med. Chem. Lett. 2003, 13,
805–808.
We appreciate the constructive contributions of Profes-
sor Takashi Takahashi (TIT), Dr. Jun Nakano (Kaken),
and Dr. Masahiro Satsukawa (Kaken) to discussions
relevant to this study. We thank Mr. Atsushi Matsuo
and Mr. Naoya Nagata for supports of computational
drug design approach. We also thank Ms. Miyako
Ohara and Ms. Kazumi Sumita for measurement of
NMR and mass spectra.
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