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COMMUNICATION
Journal Name
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DOI: 10.1039/C9CC05655F
(a) C. K. Prier, D. A. Rankic and D. W. C. MacMillan, Chem. Rev.,
deprotonation assisted by base yields the target product
019, 21, 2723-2730.
cyclopenta[b]quinoxalines 3aa
.
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In summary, we have successfully taken the in-situ-formed
nitrile (produced by oxime esters) into a visible-light-induced
radical cascade cyclization with aryl isonitriles for the synthesis
of cyclopenta[b]quinoxalines. This reaction features mild
conditions, broad functional group tolerance, and a broad
substrate scope, providing an efficient approach to the
quinoxaline derivatives.
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013, 113, 5322-5363; (b) J.-R. Chen, X.-Q. Hu, L.-Q. Lu and
W.-J. Xiao, Chem. Soc. Rev., 2016, 45, 2044-2056; (c) Q. Liu
and L.-Z. Wu, Natl. Sci. Rev., 2017, , 359-380; (d) J. A.
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Milligan, J. P. Phelan, S. O. Badir and G. A. Molander, Angew.
Chem. Int. Ed., 2019, 58, 6152-6163.
(a) X.-Y. Yu, P.-Z. Wang, D.-M. Yan, B. Lu, J.-R. Chen and W.-J.
Xiao, Adv. Synth. Catal., 2018, 360, 3601-3606; (b) X.-Y. Yu,
J.-R. Chen, P.-Z. Wang, M.-N. Yang, D. Liang and W.-J. Xiao,
Angew. Chem. Int. Ed., 2018, 57, 738-743; (c) X.-Y. Yu, Q.-Q.
Zhao, J. Chen, J.-R. Chen and W.-J. Xiao, Angew. Chem. Int.
Ed., 2018, 57, 15505-15509; (d) P.-Z. Wang, X.-Y. Yu, C.-Y. Li,
B.-Q. He, J.-R. Chen and W.-J. Xiao, Chem. Commun., 2018,
The authors acknowledge the financial support provided by the
National Natural Science Foundation of China. We also express
gratitude for the support and valuable suggestions from the
Instrumental Analysis Center of Shanghai Jiao Tong University.
54, 9925-9928; (e) B.-Q. He, X.-Y. Yu, P.-Z. Wang, J.-R. Chen
and W.-J. Xiao, Chem. Commun., 2018, 54, 12262-12265; (f)
J. Chen, B.-Q. He, P.-Z. Wang, X.-Y. Yu, Q.-Q. Zhao, J.-R. Chen
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Conflicts of interest
There are no conflicts to declare.
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(a) L. Li, H. Chen, M. Mei and L. Zhou, Chem. Commun., 2017,
53, 11544-11547; (b) D. Anand, Y. He, L. Li and L. Zhou, Org.
Biomol. Chem., 2019, 17, 533-540.
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