1
90
J.C. Kwok and D.H. Macartney
2
and Iq(CH ) Iq , supported by H NMR chemical shift
þ
1
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2
þ
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2 n
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form stable complexes with CB[7] and allow passage of
the host over the R group onto the polymethylene linker,
the modes of binding of the CB[7] in the 1:1 and 2:1 host–
guest complexes can be predicted from the length of the
polymethylene chain.
1
(
(
(
(
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Cucurbit[7]uril forms very stable 1:1 and 2:1 host–guest
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2
complexes with Iq(CH ) Iq and Iq(p-xyl)Iq cations in
þ
2þ
2
2
n
(
(
aqueous solution. With polymethylene central linkers
where n ¼ 6–10 or with p-xylene, the 1:1 complex
involves encapsulation of the central binding site, while
with shorter (n ¼ 2, 4 and 5) or longer (n ¼ 12) chains, the
CB[7] prefers to bind to the terminal isoquinolinium
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isoquinolinium groups.
3
2
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Acknowledgements
The authors acknowledge the financial support by the Natural
Sciences and Engineering Research Council of Canada and
Queen’s University for conducting this research.
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