Bioscience, Biotechnology and Biochemistry p. 1693 - 1697 (1998)
Update date:2022-07-29
Topics:
Hwang, Kwang-Jin
Park, Young C.
Kim, Hyung Jin
Lee, Jae Hyun
Furoxan derivatives 3-11 were designed and synthesized as potential fungicides. Symmetrically substituted furoxan derivatives 3a-j were prepared by dimerization of the corresponding nitrile oxide generated from N-hydroxyliminoyl chloride 2 in situ. Further functional group modifications of aldehyde 4, a key intermediate, generated furoxan derivatives 5-11. The fungicidal activities of furoxan derivatives 3-11 were observed over a broad spectrum of plant fungi at 250 ppm.
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