Synthetic Communications p. 861 - 870 (1997)
Update date:2022-08-28
Topics:
Gudmundsson, Kristjan S.
Hinkley, Jack M.
Brieger, Michael S.
Drach, John C.
Townsend, Leroy B.
An efficient large scale synthesis of 2-amino-4-chloropyridine (3) has been achieved through a modification of existing literature procedures. Compound 3 was used to prepare the previously unreported 2-amino-4,5-dichloropyridine (4). The known 2-amino-3,4-dichloropyridine (5) and 2-amino-3,4,5-trichloropyridine (6) were pepared from 3 by new routes and in higher yields than previously reported.
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