Tetrahedron Letters p. 6087 - 6090 (1998)
Update date:2022-08-25
Topics:
Watson, Brett T.
Christiansen, Gerda E.
A solid phase synthesis of substituted coumarin-3-carboxylates using the Knoevenagel condensation reaction between ethyl malonate bound to the Wang resin and ortho-hydroxyarylaldehydes is described. The reaction has been shown to proceed cleanly to give the desired products.
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