Synthesis p. 457 - 458 (1996)
Update date:2022-08-11
Topics:
D'Silva, Claudius
Iqbal, Rifat
An efficient general method for the preparation of N-arylmethylenepyrroles based on the reduction of N-acylpyrroles is reported. The reduction procedure described is sufficiently mild to make it applicable to a variety of sensitive acyl and heterocyclic acyl compounds where reduction results in cleavage of the C-N bond. The method can also be used in the preparation of pyrrole derivatives containing base sensitive protecting groups.
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(1987)