Journal of Organic Chemistry p. 5724 - 5732 (2020)
Update date:2022-08-29
Topics:
Guan, Xingchao
Li, Yulong
Xie, Zhipeng
Xie, Zhixiang
Xu, Zhezhe
The nominal enantiomer of chlorabietol B was regio- and stereoselectively synthesized from (-)-abietic acid in 13 steps. Key features of the synthesis involved an oxidative [3+2] cycloaddition to install the dihydrobenzofuran moiety and an Aldol reaction, followed by elimination and reduction steps to introduce the long chain with three cis double bonds. However, obvious differences in the NMR spectra of the synthetic and natural samples suggested that the proposed structure of chlorabietol B should be revised carefully.
View MoreShandong Yaroma Perfumery Co., Ltd.
Contact:+86- 531- 88024598
Address:7-702 Caizhi Central, 59 Gong Ye South Road, Jinan City,250101, P. R. China
Contact:13813902930 025-52714267
Address:20 Fengji Road, Yuhua Economic Development Zone, Nanjing, Jiangsu, P. R. China
Compro Shijiazhuang Fine Chemical Co., Ltd
Contact:0086-311-89689838
Address:Economic and Technological Development Zone of Shijiazhuang,Hebei
Xiamen XM-Innovation Chemical Co., Ltd
Contact:+86-592-3216205
Address:Unit Q, 11/F, No.1 Office Building, Wuyuan Bay Business Center, Huli District, Xiamen City, Fujian Province, P.R.C
Hangzhou Mole's Science & Technology Co.,Ltd.
Contact:+86-571-56880228
Address:15F Guodu development Building, NO.182 Zhaohui Road
Doi:10.3987/com-03-9921
(2004)Doi:10.1016/S0040-4039(98)01333-1
(1998)Doi:10.1002/hlca.19720550126
(1972)Doi:10.1002/1521-3749(200105)627:5<809::aid-zaac809>3.0.co;2-j
(2001)Doi:10.1016/j.tetlet.2013.05.024
(2013)Doi:10.1002/cctc.201801994
(2019)