Bioorganic and Medicinal Chemistry Letters p. 3319 - 3324 (1999)
Update date:2022-08-10
Topics:
Ishida, Junko
Wang, Hui-Kang
Bastow, Kenneth F.
Hu, Chang-Qi
Lee, Kuo-Hsiung
Twenty-six β-carbolines were evaluated for in vitro cytotoxicity in a human tumor cell line panel. Harmine (3) showed significant activity against several cell lines including three drug-resistant KB sublines with various resistance mechanisms. α-(4-Nitrobenzylidine) harmine (16) had a broad cytotoxicity spectrum (ED50 values from 0.3-1.2 μg/mL against 1A9, KB, SaOS-2, A549, SK-MEL-2, U-87-MG, and MCF-7 cells).
View MoreHangzhou Donglou Bio-nutrient Co., Ltd.
Contact:+86-571-82225795,13967112289
Address:Louta Town, Xiaoshan,Hangzhou,Zhejiang
SICHUAN ZHONGBANG NEW MATERIAL CO., LTD
website:http://www.zhongbangst.com
Contact:86-830-2585019
Address:sichuan,china
Changzhou Ruiping Chemical Co., Ltd
website:http://www.wishchem.com
Contact:+86-519-82324280
Address:No.288-1 Huacheng Road, Jintan
Contact:86-536-8866010
Address:NO.4455 EAST FUSHOU ST. WEIFANG DEVELOPMENT ZONE, SHANDONG, CHINA
Contact:0086-573-82201031
Address:Jiaxing Industrial Park, Daqiao Town, Jiaxing
Doi:10.1021/ja0483903
(2004)Doi:10.1016/j.dyepig.2016.08.063
(2017)Doi:10.1021/acs.orglett.1c01530
(2021)Doi:10.1016/S0009-2614(02)00147-1
(2002)Doi:10.1002/adsc.201800206
(2018)Doi:10.1039/c9cc05413h
(2019)