Bulletin of the Chemical Society of Japan p. 831 - 837 (1995)
Update date:2022-08-11
Topics:
Hanaki, Akira
Kinetic studies on a role of dioxygen in the copper-catalyzed autoxidation of cysteine in glycylglycine-phosphate buffers have been carried out.The rate of autoxidation was obtained by measuring the consumption of cysteine.It has been revealed that cysteine is oxidized by a "sequential mechanism".The reaction pathway can be shown by Eqs. 1, 2, 3, and 4; cysteine is oxidized not only by copper(II) species, but also by copper(I)-O2 adducts: Cu(II)-L + CyS- = L-Cu(II)-CyS- (1) L-Cu(II)-CyS- -> Cu(I)-L + CySradical (2) Cu(I)-L + O2 = L-Cu(I)-O2 (3) L-Cu(I)-O2 + Cy S- + 2H+ -> Cu(II)-L + CySradical + H2O2 (4) Here, L represents ligands including cysteine.The oxidation step (4) catalyzed by the Cu(I)-O2 species was proposed to be rate-determining.
View MoreJiangxi Dongbang Pharmaceutical Co., Ltd.
Contact:+86-795-4433603, 4433388
Address:Fengxin Industrial Park, Fengxin County, Jiangxi Province, P.R.C
Hangzhou Sartort Biopharma Co., Ltd
website:http://www.sartort.com
Contact:86-571-87039693
Address:No. 57, Tech Park Road, Hangzhou, Zhejiang, China
Zibo Linzi Darong Fine Chemical Co., Ltd
Contact:86-532-67773200; 15689126900
Address:Qidu town,Linzi district,Zibo city,Shandong province,China
ZhangJiaGang YaRui Chemical Co.,Ltd.
Contact:0512-58360968
Address:China JiangSu Province Zhang Jia Gang City YangShe Oriental Plaza Building 10 B307
Penglai Qianwei Chemical Co., Ltd.
Contact:86-535-3357802
Address:Shahelu (north), Penglai, Shandong, China
Doi:10.1063/1.121355
(1998)Doi:10.1016/j.jorganchem.2017.05.049
(2017)Doi:10.1021/ja00294a049
(1985)Doi:10.1248/bpb.18.740
(1995)Doi:10.1080/10426500008076328
(2000)Doi:10.1070/MC2001v011n05ABEH001446
(1950)