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through a generated reactive species that damages the
target protein(s). Strategies that use non-covalent immo-
bilization of structurally intact brominated furanones
for controlling biofilm formation, and for isolating pro-
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most significant result of this work is the identification
of the most important structural element of brominated
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Acknowledgments
We thank Syracuse University, the Syracuse Center of
Excellence (under the EPA Grant X-83232501-0), and
NSF-CMMI [Grant No. 0727491] for financial support.
We also thank Dr. John S. Parkinson (University of
Utah) for providing the strain of E. coli RP437. The
authors are grateful to Jiejing Qiu for helping with sta-
tistical analysis.
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Supplementary data
Supplementary data associated with this article can be
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References and notes
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