Analytical Chemistry p. 6548 - 6554 (2020)
Update date:2022-08-11
Topics:
He, Yi
Li, Hua
Liang, Jingkai
Wang, Junren
Yu, Haili
The signal of the traditional chromogenic systems is directly proportional to analyte concentration, leading to an unsatisfactory sensitivity. Herein, we report a cascade chromogenic system to realize exponential amplification of colorimetric signal through coupling chemical oxidation with photoinduced radical chain reaction. The chemical oxidation of o-phenylenediamine (OPD) by Fe3+ generates Fe2+ and photoactive 2,3-diaminophenazine (DAP). Under blue-light irradiation, DAP initiates the formation of holes and H2O2 that reacts with Fe2+ to hydroxyl radicals (·OH) and Fe3+ via an intersystem crossing (ISC) process. Moreover, the holes oxidize water to yield ·OH as well. The resulting ·OH and regenerated Fe3+ in turn oxidize OPD to yield more DAP, leading to a self-propagating reaction cycle that continues to proceed until all the OPD molecules are consumed, along with a distinct color change from colorless to yellow. Through the generation of the complex between DAP and acetone that limits the ISC process, and therefore quenches the colorimetric signal, the highly sensitive and selective naked-eye detection of acetone is achieved from 50 μM to 3 mM, with a limit of detection of 35 μM. Additionally, the feasibility of this colorimetric assay to detect acetone in real water samples is also demonstrated.
View MoreALPHA PHARMACEUTICAL CO,LTD JIANGSU
Contact:+86-527-84829968,+86-527-84829998
Address:suqian city
Hunan Dinuo Pharmaceutical Co.,Ltd.
Contact:86-731-88280100*8561
Address:Bio-pharmaceutical industrial park, Liuyang, Hunan, China
Chengdu Chengnuo New-Tech Co., Ltd
Contact:0086-028-85749078
Address:4 Jiuyang road,Jiulong industrial port,Chengdu, China
Wuhan Sunrise Pharmaceutical Technology Co., Ltd
Contact:+86-27-83314682
Address:Room 340, New material Industrial base No.17, Gu Tian Five Lu , Qiaokou District, Wuhan , China
Contact:+86-25-8776 0031
Address:3-2001 Jiaye Int'l Town, 158 Lushan Road,Nanjing, 210019, China
Doi:10.1039/c7ra06527b
(2017)Doi:10.1021/acs.joc.8b02712
(2019)Doi:10.1021/ac50067a026
(1929)Doi:10.1107/S0108270199002693
(1999)Doi:10.1071/CH9830895
(1983)Doi:10.3390/molecules24061113
(2019)