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Name	Hydroxocobalamin hydrochloride	EINECS	236-534-8
CAS No.	58288-50-9	Density	N/A
PSA	453.44000	LogP	5.88100
Solubility	N/A	Melting Point	N/A
Formula	C62H89 Co N13 O15 P . x Cl H	Boiling Point	N/A
Molecular Weight	1382.82	Flash Point	N/A
Transport Information	N/A	Appearance	N/A
Safety	26-36	Risk Codes	36/37/38
Molecular Structure		Hazard Symbols	Xi
Synonyms	Cobinamide, dihydroxide, dihydrogen phosphate (ester), mono(inner salt),3'-ester with 5,6-dimethyl-1-a-D-ribofuranosyl-1H-benzimidazole, hydrochloride;

Hydroxocobalamin hydrochloride Synthetic route

: 58288-50-9
hydroxocobalamin hydrochloride

: 18195-23-8
acetylcobalamin

Conditions

Conditions	Yield
With lithium perchlorate; acetic anhydride In methanol; water Kinetics; Electrolysis; the electrosynthesis was carried out at a potential -1.2 V vs. SCE; after that the cell was placed into ice-bath and protected from light; holding the potential at -1.2 V freshly distilled Ac2O was added; after 2 h oxygen-free acetone was added; identified by elem. anal., UV, IR spectroscopy and mass-spectrometry;	97%

Yield

With lithium perchlorate; acetic anhydride In methanol; water Kinetics; Electrolysis; the electrosynthesis was carried out at a potential -1.2 V vs. SCE; after that the cell was placed into ice-bath and protected from light; holding the potential at -1.2 V freshly distilled Ac2O was added; after 2 h oxygen-free acetone was added; identified by elem. anal., UV, IR spectroscopy and mass-spectrometry;

97%

Hydroxocobalamin hydrochloride Chemical Properties

Specified conditions are stable, away from oxides.

Hydroxocobalamin hydrochloride Uses

The same with cyanocobalamin

Hydroxocobalamin hydrochloride Production

Store in a sealed container filled with inert gas and stored in a cool, dry place. 2-8 s. C preservation.

Hydroxocobalamin hydrochloride Specification

By hydroxocobalamine and sodium pyrosulfite and replacement, nitrite and nitrosation, finally hydrochloride salt.

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