The Ligand 222, with the CAS registry number 23978-09-8, is also known as 13,16,21,24-Hexaoxa-1,10-diazabicyclo-(8,8,8)-hexacosane. It belongs to the product categories of FDG Chemicals; Azacrown Ethers; Crown Ethers; Functional Materials; Macrocycles for Host-Guest Chemistry; Crown EthersStable Isotopes; Chelation/Complexation Compounds; PET; Synthetic Reagents. Its EINECS registry number is 245-962-4. This chemical's molecular formula is C₁₈H₃₆N₂O₆ and molecular weight is 376.49. Its IUPAC name is called 4,7,13,16,21,24-hexaoxa-1,10-diazabicyclo[8.8.8]hexacosane. The product should be stored at temperature of 2-8 °C. This chemical is colourless crystals which can be used for spinning polyester filament, pulling film, manufacturing bottle, etc.

Physical properties of Ligand 222: (1)ACD/LogP: -1.34; (2)ACD/LogD (pH 5.5): -4.1; (3)ACD/LogD (pH 7.4): -1.58; (4)ACD/BCF (pH 5.5): 1; (5)ACD/BCF (pH 7.4): 1; (6)ACD/KOC (pH 5.5): 1; (7)ACD/KOC (pH 7.4): 2.57; (8)#H bond acceptors: 8; (9)#H bond donors: 0; (10)Index of Refraction: 1.502; (11)Molar Refractivity: 99.52 cm³; (12)Molar Volume: 336.8 cm³; (13)Surface Tension: 43.8 dyne/cm; (14)Density: 1.11 g/cm³; (15)Flash Point: 144.2 °C; (16)Enthalpy of Vaporization: 78.44 kJ/mol; (17)Boiling Point: 513.1 °C at 760 mmHg; (18)Vapour Pressure: 1.22E-10 mmHg at 25°C.

Preparation: this chemical can be prepared by 1,2-bis-[2-(toluene-4-sulfonyloxy)-ethoxy]-ethane and 2,2'-ethane-1,2-diyldioxy-bis-ethylamine. This reaction will need reagent Na₂CO₃ and solvent acetonitrile. The reaction time is 7 days. The yield is about 36%.

Uses of Ligand 222: it can be used to produce potassium 4,7,13,16,21,24-hexaoxa-1,10-diazabicyclo[8.8.8]hexacosane picrate at temperature of 25 °C. The yield is about 90%.

When you are using this chemical, please be cautious about it as the following:
This chemical may cause inflammation to the skin or other mucous membranes. It is irritating to eyes, respiratory system and skin. In case of contact with eyes, you should rinse immediately with plenty of water and seek medical advice. Whenever you will contact it, please wear suitable protective clothing, gloves and eye/face protection.

You can still convert the following datas into molecular structure:
(1)Canonical SMILES: C1COCCOCCN2CCOCCOCCN1CCOCCOCC2
(2)InChI: InChI=1S/C18H36N2O6/c1-7-21-13-14-24-10-4-20-5-11-25-17-15-22-8-2-19(1)3-9-23-16-18-26-12-6-20/h1-18H2
(3)InChIKey: AUFVJZSDSXXFOI-UHFFFAOYSA-N

The toxicity data is as follows: