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Linadryl hydrochloride

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Name

Linadryl hydrochloride

EINECS N/A
CAS No. 5928-69-8 Density N/A
PSA N/A LogP N/A
Solubility N/A Melting Point N/A
Formula C19H23NO2•ClH Boiling Point 402.6°C at 760 mmHg
Molecular Weight 333.89 Flash Point 128.9°C
Transport Information N/A Appearance N/A
Safety Poison by ingestion, intravenous, and intraperitoneal routes. Moderately toxic by subcutaneous route. When heated to decomposition it emits toxic fumes of NOx and HCl. Risk Codes N/A
Molecular Structure Molecular Structure of 5928-69-8 (4-[2-(diphenylmethoxy)ethyl]morpholine hydrochloride (1:1)) Hazard Symbols N/A
Synonyms

N/A

 

Linadryl hydrochloride Chemical Properties

Product Name: Linadryl hydrochloride
CAS Registry Number: 5928-69-8
IUPAC Name: 4-(2-benzhydryloxyethyl)morpholine hydrochloride
Molecular Weight: 333.85236 [g/mol]
Molecular Formula: C19H24ClNO2
H-Bond Donor: 1
H-Bond Acceptor: 3 
Flash Point: 128.9 °C
Enthalpy of Vaporization: 65.38 kJ/mol
Boiling Point: 402.6 °C at 760 mmHg
Vapour Pressure: 1.08E-06 mmHg at 25°C
Following is the molecular structure of Linadryl hydrochloride (CAS NO.5928-69-8) is:

Linadryl hydrochloride Toxicity Data With Reference

Organism Test Type Route Reported Dose (Normalized Dose) Effect Source
dog LD50 intravenous 70mg/kg (70mg/kg) BEHAVIORAL: SOMNOLENCE (GENERAL DEPRESSED ACTIVITY)

BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD

BEHAVIORAL: EXCITEMENT
Journal of Pharmacology and Experimental Therapeutics. Vol. 89, Pg. 227, 1947.
guinea pig LD50 intraperitoneal 160mg/kg (160mg/kg)   Journal of Pharmacology and Experimental Therapeutics. Vol. 83, Pg. 120, 1945.
mouse LD50 intraperitoneal 185mg/kg (185mg/kg) BEHAVIORAL: SOMNOLENCE (GENERAL DEPRESSED ACTIVITY)

BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD

BEHAVIORAL: EXCITEMENT
Journal of Pharmacology and Experimental Therapeutics. Vol. 89, Pg. 227, 1947.
mouse LD50 oral 327mg/kg (327mg/kg) BEHAVIORAL: SOMNOLENCE (GENERAL DEPRESSED ACTIVITY)

BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD

BEHAVIORAL: EXCITEMENT
Journal of Pharmacology and Experimental Therapeutics. Vol. 89, Pg. 227, 1947.
mouse LD50 subcutaneous 440mg/kg (440mg/kg) BEHAVIORAL: SOMNOLENCE (GENERAL DEPRESSED ACTIVITY)

BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD

BEHAVIORAL: EXCITEMENT
Journal of Pharmacology and Experimental Therapeutics. Vol. 89, Pg. 227, 1947.
rabbit LD50 intravenous 21mg/kg (21mg/kg) BEHAVIORAL: SOMNOLENCE (GENERAL DEPRESSED ACTIVITY)

BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD

BEHAVIORAL: EXCITEMENT
Journal of Pharmacology and Experimental Therapeutics. Vol. 89, Pg. 227, 1947.
rat LD50 intraperitoneal 185mg/kg (185mg/kg)   Journal of Pharmacology and Experimental Therapeutics. Vol. 102, Pg. 250, 1951.
rat LD50 intravenous 35mg/kg (35mg/kg) BEHAVIORAL: SOMNOLENCE (GENERAL DEPRESSED ACTIVITY)

BEHAVIORAL: EXCITEMENT

BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD
Journal of Pharmacology and Experimental Therapeutics. Vol. 89, Pg. 227, 1947.
rat LD50 oral 916mg/kg (916mg/kg) BEHAVIORAL: SOMNOLENCE (GENERAL DEPRESSED ACTIVITY)

BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD

BEHAVIORAL: EXCITEMENT
Journal of Pharmacology and Experimental Therapeutics. Vol. 89, Pg. 227, 1947.

Linadryl hydrochloride Safety Profile

Poison by ingestion, intravenous, and intraperitoneal routes. Moderately toxic by subcutaneous route. When heated to decomposition it emits toxic fumes of NOx and HCl.

Linadryl hydrochloride Specification

 Linadryl hydrochloride , its cas register number is 5928-69-8. It also can be called A 446 ; A 446 hydrochloride ; Linadryl hydrochloride ; beta-Morpholinoethyl benzhydryl ether hydrochloride ; Morpholine, 4-(2-(diphenylmethoxy)ethyl)-, hydrochloride .

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