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5928-69-8

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Basic Information
CAS No.: 5928-69-8
Name: 4-[2-(diphenylmethoxy)ethyl]morpholine hydrochloride (1:1)
Molecular Structure:
Molecular Structure of 5928-69-8 (4-[2-(diphenylmethoxy)ethyl]morpholine hydrochloride (1:1))
Formula: C19H23NO2•ClH
Molecular Weight: 333.89
Boiling Point: 402.6°C at 760 mmHg
Flash Point: 128.9°C
Safety: Poison by ingestion, intravenous, and intraperitoneal routes. Moderately toxic by subcutaneous route. When heated to decomposition it emits toxic fumes of NOx and HCl.
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    LINADRYL HYDROCHLORIDE

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  • 4-(2-benzhydryloxyethyl)morpholine hydrochloride

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    4-(2-benzhydryloxyethyl)morpholine hydrochloride

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Chemistry

Product Name: Linadryl hydrochloride
CAS Registry Number: 5928-69-8
IUPAC Name: 4-(2-benzhydryloxyethyl)morpholine hydrochloride
Molecular Weight: 333.85236 [g/mol]
Molecular Formula: C19H24ClNO2
H-Bond Donor: 1
H-Bond Acceptor: 3 
Flash Point: 128.9 °C
Enthalpy of Vaporization: 65.38 kJ/mol
Boiling Point: 402.6 °C at 760 mmHg
Vapour Pressure: 1.08E-06 mmHg at 25°C
Following is the molecular structure of Linadryl hydrochloride (CAS NO.5928-69-8) is:

Toxicity Data With Reference

Organism Test Type Route Reported Dose (Normalized Dose) Effect Source
dog LD50 intravenous 70mg/kg (70mg/kg) BEHAVIORAL: SOMNOLENCE (GENERAL DEPRESSED ACTIVITY)

BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD

BEHAVIORAL: EXCITEMENT		 Journal of Pharmacology and Experimental Therapeutics. Vol. 89, Pg. 227, 1947.
guinea pig LD50 intraperitoneal 160mg/kg (160mg/kg)   Journal of Pharmacology and Experimental Therapeutics. Vol. 83, Pg. 120, 1945.
mouse LD50 intraperitoneal 185mg/kg (185mg/kg) BEHAVIORAL: SOMNOLENCE (GENERAL DEPRESSED ACTIVITY)

BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD

BEHAVIORAL: EXCITEMENT		 Journal of Pharmacology and Experimental Therapeutics. Vol. 89, Pg. 227, 1947.
mouse LD50 oral 327mg/kg (327mg/kg) BEHAVIORAL: SOMNOLENCE (GENERAL DEPRESSED ACTIVITY)

BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD

BEHAVIORAL: EXCITEMENT		 Journal of Pharmacology and Experimental Therapeutics. Vol. 89, Pg. 227, 1947.
mouse LD50 subcutaneous 440mg/kg (440mg/kg) BEHAVIORAL: SOMNOLENCE (GENERAL DEPRESSED ACTIVITY)

BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD

BEHAVIORAL: EXCITEMENT		 Journal of Pharmacology and Experimental Therapeutics. Vol. 89, Pg. 227, 1947.
rabbit LD50 intravenous 21mg/kg (21mg/kg) BEHAVIORAL: SOMNOLENCE (GENERAL DEPRESSED ACTIVITY)

BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD

BEHAVIORAL: EXCITEMENT		 Journal of Pharmacology and Experimental Therapeutics. Vol. 89, Pg. 227, 1947.
rat LD50 intraperitoneal 185mg/kg (185mg/kg)   Journal of Pharmacology and Experimental Therapeutics. Vol. 102, Pg. 250, 1951.
rat LD50 intravenous 35mg/kg (35mg/kg) BEHAVIORAL: SOMNOLENCE (GENERAL DEPRESSED ACTIVITY)

BEHAVIORAL: EXCITEMENT

BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD		 Journal of Pharmacology and Experimental Therapeutics. Vol. 89, Pg. 227, 1947.
rat LD50 oral 916mg/kg (916mg/kg) BEHAVIORAL: SOMNOLENCE (GENERAL DEPRESSED ACTIVITY)

BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD

BEHAVIORAL: EXCITEMENT		 Journal of Pharmacology and Experimental Therapeutics. Vol. 89, Pg. 227, 1947.

Safety Profile

Poison by ingestion, intravenous, and intraperitoneal routes. Moderately toxic by subcutaneous route. When heated to decomposition it emits toxic fumes of NOx and HCl.

Specification

 Linadryl hydrochloride , its cas register number is 5928-69-8. It also can be called A 446 ; A 446 hydrochloride ; Linadryl hydrochloride ; beta-Morpholinoethyl benzhydryl ether hydrochloride ; Morpholine, 4-(2-(diphenylmethoxy)ethyl)-, hydrochloride .