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Lonomycin

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Name

Lonomycin

EINECS N/A
CAS No. 58785-63-0 Density 1.19g/cm3
PSA 170.06000 LogP 5.17390
Solubility N/A Melting Point 109-114°
Formula C44H76 O14 Boiling Point 820.8°Cat760mmHg
Molecular Weight 829.20 Flash Point 230.4°C
Transport Information N/A Appearance N/A
Safety Poison by ingestion, intravenous, intraperitoneal, and subcutaneous routes. When heated to decomposition it emits acrid smoke and irritating fumes. Risk Codes N/A
Molecular Structure Molecular Structure of 58785-63-0 (lonomycin) Hazard Symbols N/A
Synonyms

LonomycinA;2H-Pyran-2-acetic acid,tetrahydro-2-hydroxy-4-methoxy-6-[1-[9-methoxy-2,8-dimethyl-2-[octahydro-4'-methoxy-2,3'-dimethyl-5'-(tetrahydro-6-hydroxy-4-methoxy-3,5,6-trimethyl-2H-pyran-2-yl)[2,2'-bifuran]-5-yl]-1,6-dioxaspiro[4.5]dec-7-yl]ethyl]-a,3,5-trimethyl-, [2R-[2a,2(S*),3a,4b,5b,6b[S*[2S*[2S*,2'R*,3'S*,4'R*,5R*,5'R*(2S*,3S*,4S*,5R*,6S*)],5R*,7S*,8R*,9S*]]]]-;Antibiotic DE 3936;Antibiotic TM 481;Emericid;Stereoisomer oftetrahydro-2-hydroxy-4-methoxy-6-[1-[9-methoxy-2,8-dimethyl-2-[octahydro-4'-methoxy-2,3'-dimethyl-5'-(tetrahydro-6-hydroxy-4-methoxy-3,5,6-trimethyl-2H-pyran-2-yl)[2,2'-bifuran]-5-yl]-1,6-dioxaspiro[4.5]dec-7-yl]ethyl]-a,3,5-trimethyl-2H-pyran-2-aceticacid;

 

Lonomycin Chemical Properties

Molecular Formula of Lonomycin (CAS NO.58785-63-0): C44H76O14
Molecular Weight: 829.06584 g/mol
Structure of Lonomycin (CAS NO.58785-63-0):
           
IUPAC Name: (2S)-2-[(2R,3R,4S,5R,6S)-2-Hydroxy-6-[(1S)-1-[(2S,7S,8R,9S)-2-[(2R,5S)-5-[(2R,3S,4R,5R)-5-[(2S,3S,4S,5R,6S)-6-hydroxy-4-methoxy-3,5,6-trimethyloxan-2-yl]-4-methoxy-3-methyloxolan-2-yl]-5-methyloxolan-2-yl]-9-methoxy-2,8-dimethyl-1,6-dioxaspiro[4.5]decan-7-yl]ethyl]-4-methoxy-3,5-dimethyloxan-2-yl]propanoic acid

Lonomycin Toxicity Data With Reference

1.    

orl-mus LD50:45,800 µg/kg

    85GDA2    CRC Handbook of Antibiotic Compounds, Volumes 1-9. 5 (1981),482.
2.    

ipr-mus LD50:8280 µg/kg

    85ERAY    Antibiotics: Origin, Nature, and Properties. 1 (1978),801.
3.    

scu-mus LD50:37,500 µg/kg

    85GDA2    CRC Handbook of Antibiotic Compounds, Volumes 1-9. 5 (1981),482.
4.    

ivn-mus LD50:4860 µg/kg

    85ERAY    Antibiotics: Origin, Nature, and Properties. 1 (1978),801.
5.    

orl-ckn LD50:150 mg/kg

    JANTAJ    Journal of Antibiotics. 29 (1976),76-99.

Lonomycin Safety Profile

Poison by ingestion, intravenous, intraperitoneal, and subcutaneous routes. When heated to decomposition Lonomycin (CAS NO.58785-63-0) emits acrid smoke and irritating fumes.

Lonomycin Specification

 Lonomycin ,its cas register number is 58785-63-0. It also can be called Lonomycins lonomycin A ; and Emericid .

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